Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

IHO 3 > Helper CD4+ T cells > Flashcards

Helper CD4+ T cells Flashcards

1
Q

Th1 polarized by?

A

IL-12, IL-18, IFN-gamma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Th2 polarized by?

A

IL-4

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Th17 polarized by?

A

IL-1, IL-6, IL-23, TGF-beta

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Treg polarized by?

A

IL-2, TGF-beta

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Tfh polarized by?

A

IL-6, IL-21

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Th1 effector cytokines made?

A

INF-gamma, TNF-beta

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Th2 effector cytokines made?

A

IL-4, IL-5, IL-13

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Th17 effector cytokines made?

A

IL-17, IL-22

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Tfh effector cytokines made?

A

IL-4, IL-21

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Treg effector cytokines made?

A

IL-10, TGF-beta

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Th1 master transcriptional regulator?

A

T-bet

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Th2 master transcriptional regulator?

A

GATA-3

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Th17 master transcriptional regulator?

A

RORyt

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Tfh master transcriptional regulator?

A

Bcl-6

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Treg master transcriptional regulator?

A

FOX-P3

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Th1 main functions

A
  • Inflammation
  • Cell mediated immunity
  • IFNy polarizes macrophages into M1, activates, and attracts them.
  • T cell recognizes. Macrophage removes
17
Q

Th2 main functions

A
  • Polarized macrophages into M2 by IL-4 and IL-13.
  • IL-4 and IL-5 attract eosinophils.
  • Allergic and anti-helminth responses–> m2 response and stimulates switch to IgE
18
Q

Th17 main functions

A
  • IL-17 and IL-22 attract and activate many inflammatory cells
  • M1 response
  • Maintaining integrity of mucosal surface
19
Q

Tfh main functions

A
  • B cell help in germinal centers

- Help them become activated and direct B cells to undergo class-switching

20
Q

Treg main functions

A

Suppresses Th1, Th2, Th17, Tfh by contact and soluble factors (TGF-beta, IL-10)

IHO 3 (4 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions