Heart Stuff Flashcards
Pressure in the right atrium during the cardiac cycle
0-4mmHg
Pressure in the right ventricle during the cardiac cycle
25 Systolic and 4 Diastolic
Pressure in the Pulmonary Artery during the cardiac cycle
25 Systolic and 10 Diastolic
Pressure in the left atrium during the cardiac cycle
8-10 mmHg
Pressure in the left ventricle during the cardiac cycle
120 systolic and 10 diastolic
Pressure in the aorta during the cardiac cycle
120 systolic and 80 diastolic
Chronotropic effects
Heart Rate
Inotropic Effects
Strength of contraction
Dromotropic
Conduction Velocity
Parasymapthetic and blood vessels
Causes vasodilation ; acetylcholine
Frank starling law
More blood in , more blood out. More blood in ventricles stronger contraction
Sympathetic and blood vessels
Vasoconstriction ; epi and Norepinephrine
Baroreceptors
Carotid sinus, aortic sinus, right atrium
What is a baroreceptor?
Receptors relay info from blood pressure
What are the three phases of blood clotting?
Vascular spasm, platelet plug, coagulation phase
In the first phase of blood clotting what does smooth muscle do to limit bleeding
Vasoconstriction
What fibres are exposed when the blood vessel wall is damaged
Collagen fibres
What happens to collagen fibres when they are exposed
Platelets stick to them within 30-60 seconds. These platelets then release a prothrombin activator then prothrombin activates then thrombin then fibrinogen then fibrin
What does thrombin do
It’s like a molecular scissor that cuts fibrinogen into fibrin
What’s fibrins job
To reinforce the clot as the remodelling occurs to heal the damaged wall
Where are platelets formed ? Where are prothrombin formed?
Platelets = bone marrow prothrombin=liver
What part of the second phase requires vitamin k for its production
Prothrombin
How many litres of blood in the typical human
5 liters
Red blood cells
45% of blood , erythrocytes, derived from stem cells in bone marrow. Travels far in body until being replaced 120 days later.
