Heart Failure Management

Question 1

Therapeutic targets in HFpEF? (3)

Answer 1

1. Control of Congestion
2. Stabilize BP and HR
3. Improve exercise tolerance

Question 2

CHARM study results?

Candesartan HF

Answer 2

Stat sig reduction in hospitalization

No diff in all cause mort

Question 3

First principle of management of ADHF

Answer 3

Identify and tackle known precipitants of decompensation

Question 4

Parameters in HF that are associated with worse outcomes?

Answer 4

BUN >43 mg/dl
SBP <115 mmgHg
S. Crea >2.75 mg/dL
Elevated Trop I