Heart Failure II Flashcards
BNP and NT pro-BNP levels at which to get an echo if the presentation fits
Nt-proBNP - 125+
BNP - 35+
Class I recommendations
Is recommended/Indicated
Negligent if not done
Class IIa recommendations
Should be considered - weight of evidence seems to suggest efficacy but no clear consensus
Class IIb recommendations
May be considered - efficacy is less well established
Class III recomendations
Evidence is against giving - not recommended
Lifestyle modifications of HFpEF - rule of twos
Sodium restriction of 2g/day
Restrict to 2 Liters of water/day
2 lbs. weight gain/week - concerning
Class I pharm indication for a patient with HFpEF
Thiazide or Loop Diuretics
Three Thiazide diuretics
Hydrochlorothiazide, Metolazone (Very potent), Chlorthalidone (IV)
2 things to check when putting a patient on a diuretic
Potassium and renal function
Potassium replacement for lasix
10mEq of K for 20mg of Lasix
Monitoring for diuresis
Daily weights
Keep track of lifestyle modification
BMP within a week of initiation to assess kidney function
Class IIa recommendations for HFpEF
SGLT2 inhibitors -gliflozin, Jardiance, Farxiga
Class IIb recomandations for HFpEF (3)
ARNi - Entresto
Aldosterone antagonist - Spironolactone, Eplerenone
ARB -sartan
Greater benefit if LVEF closer to 50%
5 lifestyle modifications for HFrEF
Tobacco and alcohol cessation
Sodium restriction
Daily weight monitoring
Weight loss in obese patients
Increase Exercise/Cardiac rehab
6 First line, class I recommendations for patients with HFrEF in stage C
ARNi in NYHA II-III
ACE OR ARB in NYHA II-IV
Beta blocker
Aldosterone antagonist
SGLT 2 inhibitor
Diuretics as needed
Condition to add second line therapy for HFrEF
Persistent HFrEF less than or equal to 40%
Condition to begin first line therapy for HFrEF
ACA/AHA Class C!!
Second line class I recommendation for African American patients in stage III-IV HFrEF
Hydral-nitrates - Hydralazine+Nitrates
Second line class I recommendation for NYHA I-III patients with HFrEF under 35% (more than 1 year survival)
Implantable cardioverter defibrillator
Second line, class I recommendation for NYHA II-III, Ambulatory IV, LVEF 35% or less
NSR and QRS 150+ with LBBB
Cardiac Resynchronization therapy
3 Class I, 3rd Line recommendations for refractory HFrEF
Mechanical circulatory support
Cardiac transplant
Palliative care (can be initiated before stage D)
3 ACEi’s for HFrEF
Enalapril, Captopril, Lisinopril
Take baseline K and Renal fxn, then in 2 weeks