Heart Failure Diagnosis Flashcards

1
Q

3 Major Symptoms of Heart Failure

A

1) decr cardiac output due to decr organ perfusion
2) incr pulm venous pressure (left sided) –> breathlessness
3) incr central venous pressure (right sided) –> edema

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2
Q

Symptoms of Low Flow

A

1) decr cerebral perfusion (confusion)
2) decr muscle perfusion (fatigue)
3) decr gut perfusion (anorexia/wasting)
4) decr kidney perfusion (decr urine output and renal dysfunction)

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3
Q

Effect of low flow on Starling Curve

A

Shift curve downward due to decr SV for a given pressure

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4
Q

Symptoms of Left sided pressure/increased pulm venous pressure

A

1) breathlessness (dyspnea)
2) dyspnea on exertion
3) orthopnea
4) paroxysmal noctural dyspnea
5) acute pulm edema due to fluid retention/incr LA pressure so fluid from pulm vasculature enters interstitial space and then alveoli (hypoxia)

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5
Q

Effect of incr left sided pressure on Starling curve

A

given point shifts right due to incr pressure

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6
Q

Difference between orthopnea and paroxysmal noctural dyspnea

A

Orthopnea = immediate SOB lying flat

Paroxysmal Nocturnal dyspnea= delayed SOB wake from sleep and walk around

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7
Q

Why does walking around improve paroxysmal nocturnal dyspnea

A

Mobilizing edema from tissue through lymph back into blood stream

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8
Q

Why does orthopnea occur?

A

lost venous pooling of blood in the legs

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9
Q

Symptoms of incr right sided pressure/incr central venous pressure

A

1) peripheral edema in lower extrem (older)
2) ascites (younger)
3) Hepatic congestion
4) intestinal congestion

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10
Q

Right sided failure = Effect of Edema in HF on Starling forces

A

Increased central venous pressure upsets balance between Starling forces

now increase oncotic P so pump more fluid into interstitum

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11
Q

Factors that lead to worse symptoms

A

1) incr circulating volume (preload) with sodium
2) increased pressure (afterload)
3) decr inotropy
4) arrhythmia
5) incr metabolic demands (fever, infection)
6) non-adherence with HF meds

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12
Q

examples of increased pressure (afterload) that can worsen symptoms

A

1) uncontrolled HTN
2) worse aortic stenosis
3) pulm embolism

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13
Q

examples of decr inotropy that can worsen symptoms

A

1) MI

2) beta blocker or Ca2+ channel blocker

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14
Q
NYHA class 
1
2
3
4
A

1) asymptomatic
2) symptomatic with mod exertion
3) symptomatic with minimal exertion
4) symptomatic at rest

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15
Q

AHA/ACC HF stage 1

A

at risk for HF but not structural heart disease or symptoms

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16
Q

AHA/ACC HF stage 2

A

structural heart disease (prior MI, LVH and low EF) but no signs/symptoms of HF

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17
Q

AHA/ACC HF stage 3

A

structural heart disease with prior/current signs and symptoms (HFpEF) and (HFrEF)

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18
Q

AHA/ACC HF stage 4

A

Refractory HF

marked symptoms at rest

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19
Q

What is important about HF course?

A

variable course

episodic exacerbations and rarely single NYHA over time

but usually progressive decline over time

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20
Q

Physical exam

Signs of low flow

A

1) cool extremities - peripheral vasocosntriction to redirect flow to vital organs
2) tachycardia- compensate for low SV
3) low pulse pressure - low output

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21
Q

Physical Exam

Signs of elevated left sided pressure

A

1) rales due to wet alveoli opening
2) hypoxia
3) tachypnea
4) bolting upright

22
Q

PHysical exam

signs of elevated right sided pressures

A

1) edema - follows gravity (legs, sacrum, scrotum)
2) hepatic congestion
3) JVD = central venous pressure

23
Q

what does JVD measure

A

RA filling pressure

24
Q

What is JVD a sign of

A

increased central venous pressure

right heart failure

25
Q

how many Waves in JVD

A

Triphasic= 3

26
Q

A wave

A

atrial contraction

27
Q

C wave

A

closing of the tricuspid valve early in systole

28
Q

v wave

A

movement of RV annulus and tricuspid valve backward at the end of systole (before the valve opens)!

29
Q

S4 heart sound

A

before S1

atria contract forcefully to overcome stiff/hypertrophic LV

30
Q

S4 present in AFIB

A

NO NOT IN AFIB

31
Q

S4 normal or abnormal?

A

abnormal

32
Q

S3 heart sound cause

A

rapid expansion of vnetricular walls in early diastole

sudden stop in LA filling

heart vibrates during passive filling

33
Q

S3 normal or abnormal?

A

normal in young

abnormal after 40 y/o

34
Q

S3 sign of?

A

HFrEF or dilated heart

35
Q

what is summation gallop?

A

all 4 heart sounds

36
Q

Preexisting conditions to HF

A

Coronary, valve disease, HTN

Diabetes, Renal failure

37
Q

How can CXR help in HF

A

Enlarged heart in HFrEF

increased upper lobe vascular markings with acute decompensation

38
Q

What does acute pulm edema look like on CXR

A

fluffy infiltrate due to LA pressure overwhelming lymph return

39
Q

What is BNP secreted in response to?

A

Ventricular stretch (measure of preload)

Hyperadrenergic state, RAAS, ischemia

40
Q

What are assays of BNP

A

BNP- Normal <100

NT-proBNP= N terminus breakdown of BNP (inactive)
~ 6x BNP

41
Q

BNP relationship with age

A

incr age, incr BNP

42
Q

How is BNP used?

A

low BNP makes HF unlikely

in chronic HF, elev BNP not as useful

43
Q

Signs of HF in EKG

A

no direct diagnosis

1) prior MI (Q waves)
2) LVH (incr voltage)
3) diffuse disease from fibrosis or myocardial damage (LBBB)
4) arrhythmia (AFib, ventricular ectopy)

44
Q

Equation for EF

A

EF= (end diastolic volume - end systolic volume) / end diastolic volume

HFrEF = dilated + decr SV

45
Q

Advantages of echocardiogram

A

real-time
non-invasive
no radiation
cheap

46
Q

Right heart cath using Swan-Ganz

A

1) cath insert into major vein and floated to right heart into pulm artery
2) blocks branch of pulm artery to measure downstream pressure (wedge pressure = LA pressure)

47
Q

what is wedge pressure equal to?

A

LA pressure/left sided filling pressure

48
Q

PA Catheter measures what 2 things?

A

Pressures

Flow

  • fick CO
  • thermodilution CO
49
Q

In HF, what is the Fick CO and what is Thermodilution CO

A

Oxy sat aorta - oxy sat vein

Fick: In HF, lower oxy sat in vein because lower CO

Thermodilution: Longer time fo cold water to reach pulm artery because lower CO

50
Q

How to calculate resistance based on pressures and flow

A

dP = CO * R

Calculate resistance in pulm bed based on Difference between PA pressure and Wedge pressure

Calculate resistance in systemic based on difference between aortic pressure and central venous pressure