heart failure Flashcards
what HTN drug can you not use in HF
CCB
Ix: NT-proBNP for heart failure
>2000ng/L ⇒ ?
Urgent 2WW + ECHO
BNP 400-2000ng/L
6WW + ECHO
on ECHO if EF <40%
HFrEF
if on echo EF >40% + Raised BNP ⇒ ?
HFpEF
heart fialure CXR ABCDEF
Alveolar oedema (“batwing” appearance shadowing)
Kerley B lines (caused by interstitial oedema)
Cardiomegaly
Upper lobe blood Diversion
Pleural Effusions
Fluid in horizontal fissure
acute HF treatment
Acute decompensated ⇒ IV furosemide 50mg BD + Oxygen
- ACE inhibitor (e.g. ramipril)
- Aldosterone antagonist (e.g. spironolactone or eplerenone)
- Ivabradine, sacubitril-valsartan, hydralazine in combination with nitrate, digoxin and cardiac resynchronisation therapy
chronic HF treatment
Tx: ABAL + Annual influenza vaccination
ACE inhibitor (e.g. ramipril)
Beta blocker (e.g. bisoprolol)
Aldosterone antagonist when symptoms not controlled with A and B (e.g. spironolactone or eplerenone)
Loop diuretics (e.g. furosemide)
what is ivabradine
is a funny channel inhibitor which acts to slow ionic depolarisation through the pacemaker cells and therefore slow heart rate allowing for more filling time. It is used as a 4th line medication for those with an impaired LV systolic function and a higher heart rate prior to considering device therapy.
what is cor pulmonale
Right sided heart failure caused by respiratory disease
↑ Pressure & Resistance in pulmonary arteries ⇒ Pulmonary HTN ⇒ RV unable to pump blood out effectively into pulmonary arteries ⇒ Back pressure of blood in RA, VC and systemic venous system
in COPD
PE
CF
priamry pumonayr HTV
sx
Early cor pulmonale ⇒ Asymptomatic
Peripheral oedema
Raised JBP
Hepatomegaly
SoB (due to underlying chronic lung disease)
Exertional dyspnoea + Syncope
Cyanosis
Hypoxia
if diabetic what drug
ACEi first line
A 65-year-old man with heart failure presents to his GP with some questions about some of his medications. He would like to know which of his drugs will help him to live longer and not just improve his symptoms.
What is the most appropriate response?
ACEi BB and spirono