Heart failure Flashcards

1
Q

What is cardiac output

FOrmula

A

amount of blood theheartpumps through the circulatory system in a minute – expressed in litres per minute

Cardiac Output (CO) = Heart Rate (HR)×Stroke Volume (SV))

Stroke volume- ml heart pumps out L ventricle in one pump

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2
Q

What is ejection fraction

A

s a measurement, expressed as a percentage, of how much blood the left ventricle pumps out with each contraction.

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3
Q

What’s a normal EF
What’s not normal
What’s borderline

A

Above 50%
Below 40% (HF)
40-50

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4
Q

How to classify HF

A

Systolic dysfunction- HFrEF (insufficient pumping action or impaired contraction. Occurs when EF <40%

Diastolic dysfunction (insufficient filling of the ventricle due to decreased compliance and impaired relaxation)

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5
Q

Causes of HF

A

Ischaemic heart disease
Chronic hypertension
Dilated cardiomyopathy
Myocarditis

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6
Q

Causes of diastolic dysfunction

A
HTN with LVH
Restrictive cardiomyopathy
Hypertrophic cardiomyopathy
Fibrosis 
Amyloidosis 
Sarcoidosis
Constrictive pericarditis
Haemochromatosis 
Aging
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7
Q

Symptoms of HF

A

Shortness of breath (dyspnea) when you exert yourself or when you lie down
Fatigue and weakness
Swelling (oedema) in your legs, ankles and feet
Rapid or irregular heartbeat
Reduced ability to exercise
Persistent cough or wheezing with white or pink blood-tinged phlegm
Increased need to urinate at night
Swelling of your abdomen (ascites)
Very rapid weight gain from fluid retention
Lack of appetite and nausea
Sudden, severe shortness of breath and coughing up pink, foamy mucus( In keeping with pulmonary oedema)
Chest pain if your heart failure is caused by a heart attack

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8
Q

L sided failure

A

Paroxysmal nocturnal dyspnoea
Restlessness (as poor perfusion of brain)
Defunctioning of kidney (undwrperfusion)
Pulmonary congestion- cough, crackles, blood sputum tinge

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9
Q

R sided failure

A
Fatigue 
Peripheral venous pressure 
Ascites 
Enlarged liver and spleen 
Distended JVP
Anorexia and complaints of GI distress
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10
Q

Clinical signs of L sided heart failure

A

Crackles in lung bases initially then throughout lung field if left untreated.
Gallop rhythm (an abnormal heart rhythm marked by the occurrence of three distinct sounds in each heartbeat like the sound of agallopinghorse.)
Laterally displaced apex beat
Signs of Right sided heart failure:

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11
Q

Clinical signs of R heart failure

A
Signs of Right sided heart failure: 
Remember that in right sided heart failure the blood backed up will cause swelling to the veins, interstitial space and organs.
- Lower limb and sacral pitting edema	
- Raised Jugular Venous pressure (JVP) 
- Organomegaly (Liver and spleen)
- Ascites
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12
Q

Investigations

A
ECG
CXR
BNP
cardiomyopathy
Echocardiogram

May need MRI/angiography/dobutamine stress ECHO/ Trans-oesophageal echo

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13
Q

Time course of HF

A

Acute or chronic

Or can be acute on chronic

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14
Q

Goals of treatment

A

identify / treat any cause (valvular disease; IHD)

Reduce cardiac workload

Increase cardiac output

Counteract maladaptation

Relieve symptoms

Prolong quality life – reduce hospitalization

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15
Q

Management of acute heart failure (sudden onset pulmonary oedema)

A

Sit the patient up!
High flow oxygen
IV diuretics (furosemide) at escalating doses
Consider IV nitrates (caution in hypotension and heart failure secondary to severe aortic stenosis!)
(Consider iv opiates and antiemetics)
Consider non-invasive ventilation (CPAP)
Consider inotropic support
Consider device therapy (intra-aortic balloon pump/Impella device)
Consider referral for Left Ventricular Assist Device (Bridge or destination therapy) or Cardiac transplantation

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16
Q

Management of chronic heart failure

A

Diuretics for symptoms
Ace Inhibitors or ARBs if ACEI not tolerated
Betablockers (not in acute decompensation or in patients with signs of pulmonary oedema)
Mineralocorticoid Receptor Antagonists (MRA)
Ivabridine
ARNI (Entresto)
ISMN/Hydralazine (if cannot take ACE i or ARB)
Consideration of CRT/ICD
Consideration of cardiac transplantation