hearing Flashcards

1
Q

what is sound

A

varying distribution of air molecules in space over time, about a fixed point in space

molecules affect neighbouring molecules, giving rise to propogation of sound wave

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2
Q

how can sound be represented, what are its features

A

by a sin (as in cos and sin) wave

the period is the time taken for the wave to cross the centre line 3 times (go above and below it once each), or as seen in a sin wave between 0 and 360 degrees

amplitude is distance between top of peak and bottom of trough

frequency = 1/period, measured in Hz

pitch of sound is determined by frequency, loudness is determined by amplitude

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3
Q

what is human hearing range

A

20-20,000 Hz but most sensitive range is 1,000-4,000Hz

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4
Q

how is sound pressure calculated

A

sound pressure level (dB)= 20 x log (Pt/Pr)

Pt is test pressure (the sound pressure)

Pr is the reference pressure (20microPa), 1Pa = 1N/M^2

Pr is the threshold (just audible) sound pressure

if sound is 10 times Pr then it is 20dB, if it is 100 times Pr then it is 40dB

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5
Q

describe anatomy and function of the outer ear

A

outer ear is known as auricle or pinna

consists of:

the helix (large back part of the ear)

the lobule (ear lobe)

the concha (hard protrusion right in front of the hole)

external auditory meatus

function of the auricle: gathers sound and thus transforms sound pressure at the tympanic membrane, amplifies sound and filtration of sound which aids in sound localisation

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6
Q

describe anatomy and function of the middle ear

A

function: transfers sound energy from the external environment to the cochlea

comprises of the tympanic membrane (the ear drum), the ossicles, the middle ear muscles and the eustachian tube

the ossicles reside just inwards and above of the tympanic membrane

the eustichian tube is inwards of the tympanic membrane and goes downwards

middle ear muscles in order of outwards to inwards and downwards: malleus, incus, stapes and tensor tympani

the function of the ossicles is lever action and pressure amplification

reflex contraction of middle ear muscles can reduce ossicle movement which has protective function

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7
Q

what is impedence matching

A

the difference in area between tympanic membrane and oval window compensates for impedance mismatch between air and cochlear fluid, provides up to 30dB sound increase at 2.5Khz, since tympanic membrane has higher area the pressure will be higher at oval window

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8
Q

what does damage of different parts of ear result in

A

middle ear damage is termed conductive deafness

inner ear damage is termed nerve deafness

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9
Q

what is function of the inner ear

A

function of the cochlea (inner ear): splits sound into simple components, amplifies signal, transduces mechanical vibrations into action potentials

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10
Q

what is the basilar membrane

A

the basilar membrane is tuned (has a inwards helical shape (like snail shell) which gets thinner as you go in) this allows cochlea to seperate frequencies, since at the apex the membrane is wide thin and flexible, at the base (outside) it is narrow, thick and stiff, there is a place on the BM at which each frequency is processed (place principle)

the thinner the membrane, the lower the frequency sound it detects, so the base detects 20,000 Hz and apex detects 20Hz

travelling wave displaces chochlear fluids which cause basilar membrane to move up and down

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11
Q

where are sensory hair cells located in the ear

A

in the organ of corti, in the inner ear

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12
Q

describe the inner ear anatomy

A

primary afferent neurones of cranial nerve 8 synapse onto inner hair cells (IHCs)

in the middle of inner ear is the basilar membrane, it seperates on one side the scala tympani and on the other side the scala vestibuli and scala media

scala media has contact with basilar membrane, scala vestibuli does not, it is seperated from scala media by reissner’s membrane

in scala media is the tectorial membrane which contacts the inner and outer hair cells

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13
Q

what effects inner hair cells receptor potentials

A

basilar membrane movements drive receptor potential

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14
Q

describe the pattern of innervation in the inner ear

A

type 1 auditory nerve fibres are connected to IHCs, they have the same tuning as the part of the basilar membrane to which they are connected

tonotopic map is carried into the central auditory system

selective innervation pattern of afferent neurones allows for chochlear frequency map

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15
Q

how many auditory nerve fibres are there in humans, how are they distributed

A

roughly 30,000

95% are type 1; myelinated, synapse with IHCs, there are up to 20 afferents per IHC however each afferent only synapses one IHC

5% are type 2; unmyelinated, synapse onto OHCs, one fibre synapses between 5-100 OHCs

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16
Q

where are cell bodies of the auditory nerve fibres

A

cell bodies are in the spiral ganglion

17
Q

how many outer/inner hair cells are there, where do efferent fibres innervate the inner ear

A

3,500 IHCs and 12,000 OHCs in the human cochlea

there are also efferent fibres which synapse onto OHCs and on the afferent fibre terminals

18
Q

what is ensemble code

A

formed from a pool of information across many auditory nerve fibres

19
Q

how do auditory nerve fibres show phase locking

A

they show phase locking up to 3000 Hz to form a temporal code

20
Q

how is sound amplified in the inner ear

A

OHCs amplify basilar membrane vibrations, increasing sensitivity and frequency selectivity

receptor potentials drive length changes in outer hair cells

active processes are evident in otoacoustic emissions

21
Q

what is function of OHCs

A

they are choclear amplifiers, they give sharp frequency selectivity/tuning

efferent nerve activity acts on OHCs and can alter basilar membrane mechanism

22
Q

what is function of IHCs

A

transduce sound signal and transmit it to CNS via auditory nerve fibres