Headaches quiz - Ch 148 (billie) Flashcards
What are the life threatening central nervous system infections that we are worried about in the ED
- bacterial meningitis
- viral encephalitis
- brain abscess
- spinal epidural abscess
what is aseptic meningitis
when inflammation of the meninges is due to causes other than bacterial infection such as drug rxn, rheumatologic conditions, or nonbacterial infections (viral/funal)
what are the MCC of aseptic meningitis
enteroviruses and echoviruses
what is the clinical triad of meningitis
- fever
- neck stiffness
- AMS
less than 1/2 of paients present with all three initially!
headache is also a common symptom
what physical exam findings should you look for in CNS infections
- nuchal rigidity
- kernigs sign (pain in back and legs w flexion of hip and ext knee)
- brudzinski’s sign (flexion of hips w passive flexion of neck)
- cranial nerve palsy
- skin for petechiae, splinter hemorrhages (systemic infection signs)
what is encephalitis
infection of the brain parenchyma that causes inflammation within the CNS. often caused by VIRAL infection
what is the most treatable cause of encephalitis
herpes simplex virus (HSV)
pts w encephalitis may mimic what other diagnosis? what additional symptoms should you look for to differentiate these?
may mimic meningitis (neck stiffness, fever, headache, AMS)
look for other symptoms such as:
- cognitive deficits
- psychiatric symptoms
- seizures
what is the diagnostic study of choice for suspected meningitis or encephalitis
lumbar puncture
when is CT brain indicated in suspected encephalitis or meningitis
when AMS, new onset seizures, immunocomp pts, focal neuro signs, or papilledema are present.
order BEFORE LP in these scenarios due to risk of CI to LP such as occult mass or signs of brain shift/herniation
when are blood cultures particularly helpful in the diagnosis of meningitis and encephalitis
to identify bacterial pathogens when empiric antibiotics are given prior to LP
in patients 50 years old or less with suspected bacterial meningitis, what is the empiric treatment?
3rd gen ceph (ceftriaxone(rocephin)) + vanc
add dexamethasone to decrease mortality and nero probs
what patients are at risk for listeria monocytogenes meningitis and what is the empiric treatment for these patients
50+years, pregnant, alcoholic, immunocomp
tx:3rd gen ceph (ceftriaxone(rocephin)) + vanc + ampicillin
add dexamethasone to decrease mortality and nero probs
what is the empiric treatment for patients with suspected encephalitis
IV acyclovir
if CSF analysis comes back + for encephalitis and the cause is CMV, what is the treatment
IV ganciclovir