Headaches

Question 1

What is the mechanism of triptans?

Answer 1

Selective 5HT1b-d agonists; penetration of CNS, constriction of extracerebral intracranial vessels, inhibition of trigeminovascular system

Question 2

What 3 classes of drugs are used for preventive migraine treatment?

Answer 2

antidepressants (SSRIs), antihypertensives (beta blockers- propranolol most used), antiepileptic (valproic acid and topiramate most used)

Question 3

What can botox be used to treat?

Answer 3

chronic migraine headaches (specific injection protocol)

Question 4

What is mainstay preventive treatment for chronic tension type headaches?

Answer 4

TCA- amitriptyline

Question 5

What is used for short-term cluster headache treatment?

Answer 5

steriods- prednisone or methylprenisolone

Question 6

What is used for long-term prevention of cluster headaches?

Answer 6

Verapamil most commonly; topiramate, valproic acid, lithium