Headaches Flashcards

1
Q

Mcc of secondary headache

A

Systemic infection

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2
Q

Mcc of primary headache

A

Tension headache

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3
Q

Headache common in pregnancy and post pregnancy

A

CVThrombosis

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4
Q

Pain sensitive structures in cranium

SMD FP

A

Scalp
Meningial arteries
Dural sinuses

Falx
Prox seg of pial arteries

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5
Q

Pain insensitive structures in cranium

VCPB

A

Ventricle ependyma
Choroid plexus
Pial veins
BRAIN PARENCHYMA**

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6
Q

Age and sex for GCA

A

F»M (4:1)

Exclusively 50+ years

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7
Q

C/f of GCA

A

Headache (throbbing/stabbing)

Scalp tenderness (pillow+)

Jaw claudication

Pain and stiffness of back shoulders
(POLYMYALGIA RHEUMATICA)

BLINDNESS** (PCA involvement)
Irreversible

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8
Q

Temopral artery biopsy GCA

A

2-5cm needed
Segmental lesions
PANARTERITIS (all three layers)
Giant cells

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9
Q

Rx GCA

A

Prednisone

Ch3pred if visual loss
(AMAUROSIS FUGAX)- Also S/I HOLLENHURST PLAQUES IN RET ARTERY*

Aspirin (for thrombotic cx)

Tocilizumab (IL6)

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10
Q

C/f pseudotumor cerebri

A

Young obese female

ICT+
Papilledema
Headache (awakening/morning/inc on cough sneeze bend fwd)

NO neural deficit
NO hycocephalus

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11
Q

Etiology of PTC

A

IDIOPATHIC (mc)

CEREBRAL VENOUS HTN
(Dt sagittal venous thrombosis—delta sign)

MENINGITIS

IATROGENIC

METABOLIC (hypoPTH/ Cushings/ Addison)

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12
Q

Iatrogenic causes of PTC

A

Hypervitaminosis A ***

Expired tetracyclines

FQ

Estrogen

Lithium

Lead

Amiodarone

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13
Q

Rx PTC

A

Acetazolamide (decrease csf production)

LP shunt

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14
Q

Which headache a/w depression

A

Tension headache

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15
Q

Rx tension headache

A

<15/m = NSAIDS

> 15= TCA (Rx depression)

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16
Q

Migraine diagnostic criteria

A

DURATION(4-72 hrs)

QUALITY OF HEADACHE- PUMA (Puls/uni/mod-sev intensity/ aggravation on movement)
(Minimum 2)

NAUSEA / VOMITING (any 1)

PHOTOPHOBIA(blurring)/ PHONOPHOBIA (any1)

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17
Q

Mc symptom of migraine

A

Photophobia»light headed>scalp tender

18
Q

Migraine with aura called as

A

Classical migraine

19
Q

Migraine without aura called as

A

Common migraine

20
Q

Cortical spreading depression theory

A

Trigger—Monoaminergic areas of brain+(brainstem and hypothalamus)—secrete vasoactive peptides at Trigeminal nerve nucleus—TGN carries signal to VB and P nucleus of thalamus—Cerebral Vasodilation—Vasoconstriction(late)

21
Q

Triggers of migraine

A
Menses
Red wine
Hunger
Insomnia
Bright light
Stress
22
Q

Vasoactive peptides of migraine

A

CGRP***
(Calcitonin Gene Related Peptide)

NO
VIP
Substance P

23
Q

Cerebral Vasodilation c/f

A

Esp in occipital lobe

FORTIFICATION SPECTRA
Flashes of light

24
Q

C/f of Vasoconstriction

A

Scotoma

Negative symptom

25
Q

Speed of spread of meningeal irritation due to vasodilation

A

2-4mm/min

Occ—par—tempo—frontal

26
Q

5HT4 agonist Rx

A

Non selective—ERGOTAMINE (Coronary S/E)

Selective— 1B/1D = Triptans
1F = lasmi-DITANS

Triptans best = RIZATRIPTAN
Long acting and tolerable= Nara/Frova

27
Q

Theories of migraine

A
Cortical depression
Serotonin deficiency
Dopamine stimulation (rx metoclop)
28
Q

Prophylaxis of migraine (5-6months)

ABCD

A

AED- Valproate/Gabapentin
BB- Propanolol
Ccb- FLUNARIZINE** (Also a DA depletor)
Depressants- TCA

29
Q

CGRP antagonists

A

RemaGEPANT

UbroGEPANT

30
Q

CGRB Ab

FEEG

A

Erenumab

Eptinumab

Fremanazemab

Galacnezemab

31
Q

Braintumour c/f

A

ICT

Projectile vomiting***

32
Q

Cluster headache sex preference and age

A

M»F

20-50y

33
Q

Cluster headache pain characteristics

A

Retro-orbital
U/L
Alcohol ppt
Awakens sleep

1-8 attacks/d for 1-8 weeks—relapse after 1 year
PERIODICAL**

34
Q

Autonomic symptoms of CH

U/L only

A

Larimation
Ptosis
Rhinorrhea
Conjunctival congestion

35
Q

Lesion of Cluster headache is in

A

HYPOTHALAMUS

36
Q

Rx CH

A

O2 (100%) -10 minutes
Sumatriptan
VNS (Vagal nerve stimulation)

37
Q

Prophylaxis of CH DOC

A

Verapamil»>prednisone»Lithium

38
Q

Trigeminal Autonomic Cephalgias

A

CH

PH paroxysmal Hemicrania
SUNCT- Short Lasting Neuralgia with Conjunctival Tearing

39
Q

Features of TAC

A

Anterior and Middle cranial fossa (distribution of TGN)

A/w pituitary tumors

Autnomic symptoms +++

Migranous symptoms (nv photo phono)

40
Q

Paroxysmal Hemicrania freq/durN/rx

A

<20 attacks/d

2-30 min (CH = 15-180min)

INDOMETHACIN

41
Q

SUNCT freq/durN/ trigger / rx

A

> 20 attacks per day
5-240 seconds
CUTANEOUS TRIGGER**
Lidocaine