Head Neck Thyroid Parathyroid Flashcards
Mucous retention cyst of sublingual gland
Ranula
Benign tumor of the tongue derived from schwann cells?
Treatment?
Giant cell myoblastoma (ABRIKOSSOF TUMOR)
Tx: wide excision
Arise from dental lamina associated with impacted tooth
Presents as painless mandibular mass
Xray: “soap bubble appearance”
Ameloblastoma
Cyst of oral mucosa due to rupture of ductal system hence submucosal accumulation of mucus
Mucous retention cyst
Where does left Recurrent LN crosses?
Aorta
Where does right Recurrent LN crosses?
Subclavuan artery
In radionuclide imaging, what kind of iodine is used to see residual thyroid after surgery or for metastatic cancer?
Iodine-123 (half life: 12-14 hours)
In radionuclide imaging, what kind of iodine is used to screen and treat well differentiated thyroid cancers?
Iodine-131 (half life: 8-10 days)
Adverse effect of methimazole
Congenital aplasia
Adverse effect of anti-thyroid drugs
Granulocytopenia/ agranulocytosis
Peripheral neuritis
Aplastic anemia (irreversible)
Action of PTU and methinazolr
Inhibit iodine organification and coupling of iodotyronine
PTU: also inhibit peripheral conversion of T4 to T3
Disadvantage of Radioactive iodine therapy
Progression of ophthalmopathy
Increased rate of cardiovascular mortality
Advantage of RAI in hyperthyroidism
Eurhyroid in 2 months
Absolute contraindication for RAI
Pregnant and breastfeeding
Indication of RAI
Elderly male with small-moderate goiters
relapse after surgery
What are the components of hartley-dunhill procedure?
Total ipsilateral lobectomy
Isthmusectomy
Contralateral subtotal thyroidectomy
Signs and symptoms are sinilar to grave’s but extrathyroidal sx are absent
Toxic multinodular goiter
Occurs in young patient with long standing nodule with hyperthyroidism
PLUMMER’s disease (Toxic Adenoma)
If with recurrent acute thyroiditis, suspect what anomaly?
3rd branchial cleft anomaly
Persistent PYRIFORM SINUS fistula
Thyroiditis common in children, preceded by URTI
Acute suppuratice thyroiditis
Kind of thyroiditis viral in origin
Subacute thyroiditis PAINFUL type
Sub acute Thyroiditis that is auto immune in origin
Subacute thyroiditis PAINLESS Type
Most common inflammatory disorder of thyroid gland
Hashimoto’s/ Lymphocytic/Chronic thyroiditis
Leading cause of hypothyroidism
Hashimoto’s/ Lymphocytic/Chronic thyroiditis
Hard woody thyroid gland
Painless hard anterior mass
Compressive
REIDEL’S thyroiditis/ invasive fibrous thyroiditis
Single most important test in evaluation of thyroid nodules
FNAB (gauge 23 needle)
Diagnostic procedure for HURTLE CELL and FOLLICULAR CA
Tissue biopsy/ frozen section
They can’t be diagnosed with FNAB
In FNAB of thyroid nodule, components of optimum cytology
6 follicles
10 cells/ follicle
In 2 aspirates
After thyroidectomy, how many weeks will you give RAI?
6 weeks
Dose of maintenance LT4 post op
1.5 mcg/kg
Test to request after TSH in the evaluation od thyroid nodule
Euthyroid/ hypothyroid: FNAB
Hyperthyroid: RAI SCAN
Diagnostic for non palpable thyroid nodule
Ultrasound
Management of simple thyroid cyst
Aspiration (up to 3x)
But for >4cm and complex cyst: unilateral lobectomy
Management for colloid adenoma
3cm: lobectomy+isthmusectomy
Common thyroid CA in children, radiation exposure and iodine sufficient
Papillary CA
Orphan annie nuclei
Psamomma bodies
Papillary thyroid CA
Type of thyroid carcinoma with presence of vascular invasion
Follicular thyroid CA
Marker for recurrence of well differentiated (papillary/follicular) thyroid CA
Thyroglobulin
Thyroid CA secondary to germ line mutation at the ret proto oncogene
Medullary thyroid CA
Arisea from parafollicular cells at superolateral lobe of thyroid gland
Medullary thyroid CA
Hormones produced in medullary thyroid CA
Calcitonin CEA CGRP Histaminidase Serotonin
Pre malignant lesion of medullary thyroid CA
Chief cell hyperplasia
Diseases in MEN 2A
Medullary thyroid CA
Pheochromocytoma
Prinary hyperparathyroidism
Diseases in MEN 2B
Medullary thyroid CA
Pheochromocytoma
Marfanoid habitus
Mucocutaneous ganglioneuromatosis
Diagnostics for postoperative follow up of medullary Thyrois CA
Annual CEA and calcitonin
When is total thyroidectomy done in MEN 2A patients?
Before 6 years old
When is total thyroidectomy done in MEN 2B patients?
Before 1 year old
Arises usually from hashimoto’s thyroiditis with similar symptoms with anaplastic carcinoma but painless
Thyrois lymphoma
Tx: CHOP
Most common metastasis to thyroid
Renal cell CA
Bleeding under platysma
Bull neck deformity
Involves middle thyroid vein
Blood supply of parathyroid
Inferior thyroid artery
Most common location of supernumerary glands
Thymus
Most common location of ectopic parathyroid
Paraesophageal
Most common cause of primary hyperparathyroidism?
Parathyroid adenoma
2nd: hyperplasia
Primary hyperparathyroidism pentad
Kidney stones Bone pains Abdominal groans Psychic moans Fatigue overtone
Treatment for parathyroid CA
En bloc resection + ipsilateral thyroid lobe
Mainstay treatment for hypercalcemic crises
IV 0.9 saline hydration
3 esophageal narrowing
Cricopharyngeus
Left mainstem bronchi
Diaphragmatic hiatus
Hallmark of intestinal metaplasia in barret’s esophagus
Intestinal goblet cells
30-100x risk for adenoCA
Gold standard diagnostic for persistent GERD
24 hour pH monitoring