Head and Neck / Craniofacial; both including embryology Flashcards

1
Q

Describe gustatory sweating

A
  • Also called Frey’s syndrome
  • sweating while eating
  • during parotid gland surgery, can get abnormaly reinnervation betwee sympathetics to sweat glands and parasympathetic to the parotid gland from the auriculotemporal nerve,
  • as well as parasympathetics crossing to facial sweat glands when raw parotid gland is opposed to skin
  • therefore eating which should stimlate the parotid gland actually stimulates sweat glands
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2
Q

describe relationship between arteries in neck, and cranial nerves

A
  • facial artery, at origin at facial-lingual trunk from external carotid, travels UNDER cranial nerve XI (hypoglossal; injury results in ipsilateral tongue paralysis)
  • facial artery at lateral mandible is related to the marginal mandibular branch of CN VII
  • superior laryngeal artery is related to recurrent laryngeal nerve (vocal cord paralysis)
  • common carotid artery is related to vagus nerve (vocal cord paralysis, other)
  • occipital artery is related to SAN
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3
Q

describe type of anatomy/joint of the TMJ

A
  • ginglymoarthroidal joint, which means there is sliding component (superior portion - glenoid to disc) and hinge component (inferior portion - disc to condyle)
  • early mouth opening is hinge (20mm), from inferior portion
  • late / wide mouth opening is helped by translation / sliding forward, from superior portion
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4
Q

List ways to identify the facial nerve as it emerges from the styloid foramen

A
  1. If the tragal cartilage is followed to its deep end, it terminates in a point. The nerve is 1 cm deep and inferior to this “tragal pointer”. There is an avascular plane right on the anterior surface of the tragus that allows a safe and quick dissection to this tragal pointer.
  2. By following the posterior belly of the digastric posteriorly, the nerve is found passing laterally immediately deep to the upper border of the posterior end of the muscle.
  3. If the anterior border of the mastoid process is traced superiorly, if forms an angle with the tympanic bone. The nerve bisects the angle formed between these two bones (at the tympanomastoid suture).
  4. By feeling the styloid process in between the mastoid bone and the posterior border of the mandible. The nerve is just lateral to this process.
  5. By following the terminal branches of the nerve proximally
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5
Q

How many bones are there in the skull? List them

A
  • 22 bones
  • Neurocranium
    • Occipital (1)
    • Parietal (2)
    • Temporal (2)
    • Frontal (1); orbit
    • Sphenoid (1); orbit
    • Ethmoid (1); orbit
  • Viscerocranium (face)
    • Lacrimal (2); orbit
    • Zygoma (2); orbit
    • Maxilla (2); orbit
    • Palatine bone (2); orbit
    • Nasal bones (2)
    • Inferior nasal concha (2)
    • Vomer (1)
    • Mandible (1)
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6
Q

what types of structures are derived from ectoderm, mesoderm and endoderm?

A
  • Ectoderm: Nervous system, skin (epidermis and appendages), and neural crest cells and derivatives
  • Mesoderm: Bone, cartilage, muscles, connective tissue (dermis), dura mater, heart, vessels, blood, reproductive organs, and genitourinary system
  • Endoderm: Gastrointestinal and respiratory lining and digestive organ parenchyma
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7
Q

what are the Carnegie stages?

A

· based on development; from gestation to birth; standardized system of 23 stages

· defined by morphology, age, somites, length

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8
Q

What is a somite?

A
  • segmental mesodermal swelling around neural tube
  • 42 to 44 pairs are present at end of 5th week (# used to date embryo); 3 subtypes:
    • myotome (tendon and bone)
    • dermotoma (dermis of neck and trunk)
    • sclerotome (vertebrae, base of skull and ribs)
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9
Q

what are neural crest cells?

A
  • pluripotent cells of ectodermal origin
  • form at jxn of neural tube and surface ectoderm
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10
Q

how do the pharyngeal (branchial) arches form?

A
  • form from migrating NCC & surrounding pharyngeal mesoderm and endoderm
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11
Q

describe the components of each of the branchial arches

A

Arch

Muscle

Cartilage

Artery

Nerve

I - mandibular

(MxP, MdP)

Mastication

Mylohyoid

Anterior digastric

TVP

tensor tympani

Meckel’s: all disappear except Md condyle and malleus

Also: maxilla, incus, greater wing sphenoid

maxillary

V

II - hyoid

Facial expression

posterior digastric

stylohyoid, stapedius

Reichert’s: lesser horn and upper body hyoid

also: stapes, styloid process, stylohyoid ligament,

stapedial

VII

III - pharyngeal

stylopharyngeus

greater horn and lower body hyoid

carotid

IX

IV - laryngeal

velar: LVP, PP, PG, sup constrictor (ie not TVP)

pharyngeal contricters

laryngeal muscles

thyroid cartilage

aortic arch, R subclavian

X

V

(sometimes grouped w/ IV)

intrinsic laryngeal muscles except cricothyroid

cricoid, arytenoid, corniculate

L pulmonary and DA, R subclavian

recurrent

laryngeal

VI

SCM, trapezius

/

/

XI

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12
Q

describe the branchial pouches and their derivatives

A

Pouch

Derivative

I

middle ear, internal auditory canal

II

palatine tonsil

III

inferior parathyroid, thymus

IV

superior parathyroid (IV migrates above III)

V

ultimobranchial body (C cells)

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13
Q

briefly define 2 methods of bone formation

A
  • ntramembranous ossification: Cartilaginous precursors resorb; mesenchymal cells directly differentiate into osteoblasts without a cartilaginous intermediate
  • Endochondral ossification: A cartilaginous template is directly and gradually replaced with a bony matrix
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14
Q

describe components of the skull that develop from intramembranous ossification compared to endochronral ossification

A
  • Neurocranium - encasing, protecting the brain
    • Membranous neurocranium - cranial vault; via IMO of NCCs
      • paired frontal, squamosal, pareital, and upper occipital
    • Cartilaginous neurocranium - cranial base
      • via EO of mesodermal origin
      • sphenoid and ethmoid, mastoid and petrous temporal bone, base of occipital bone
  • Viscerocranium - bones of facial skeleton
    • Membranous viscerocranium; via IMO
      • derived from the MxP of the 1st branchial arch: squamous temporal, maxilla, zygoma, palatine, vomer and palatine bone
      • derived from MdP of 1st branchial arch: mandible (except condyles)
    • Cartilaginous viscerocranium
      • 1st arch - meckel’s - condyle of mandible, malleus
      • 2nd arch - reichert’s - stapes
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15
Q

discuss the embryological facial prominences, and what the derive to become

A

Prominence

Gives Rise to

FNP

Forehead, nasal dorsum

MNP, LNP

(from ventral, caudal movement)

MNP

central nose and nasal septum, pre-maxilla, primary palate, philtral column and midlip

(from fusion of bilateral MNP)

LNP

nasal ala (incl cartilages)

MxP

secondary palate, lateral lip (lat to philtral column), lateral maxilla, nasolacrimal duct, cheeks, zygoma

(MxP first meets/fuses with LNP then MNP; fusion leads to contuity between lip, nose, palate)

MdP

Lower lip, meckel’s cartilage (mandible, malleolus), lower face

mandible from intramembranous ossification of meckel’s; exception are condyles by endochondral ossification

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16
Q

discuss the embrylogical development of the facial promenences, and specifically the perioral and palate development, as it relates to cleft lip and palate formation

A

Week

Occurrence

Formation

4

MNP, LNP form from the FNP

Nares

4-6

Maxillary prominence grows medially to merge with MNP; paired MNP in midline

Upper lip and primary palate (paired MNP in midline = medial palatine process)

6

Paired vertical projections of maxillary prominences from either side of the tongue

Lateral palatal shelves (lateral palatine processes)

7

Tongue withdraws, palatine processes “swing” into a horizontal position (R before L)

Secondary hard palate

8

Intramembranous ossification of hard palate

Lateral palatal shelves and premaxilla

7-12

Growth centres in the caudal end of the palatal shelves sequentially merge and remodel

Soft palate

17
Q

describe the general pathogenesis of clefts of face, lip, palate

A
  • Cleft lip: failure of fusion between the MxP and the MNP, mesenchymal tissue fails to merge
    • midline cleft lip: failure of fusion of paired MNP
  • Cleft of primary palate: failure of fusion of medial and lateral palatine processes
  • Cleft of secondary palate: Failure of elevation/contact/adhesion or failure of fusion of lateral palatine processes to each other / nasal septum
18
Q

describe innervation of tongue

A
  • anterior 2/3 from 1st branchial arch; innervated by CN V (sensation) and CN VII (taste)
  • posterior 2/3 from 3rd branchial arch; innvervated by CN IX for sensation and taste
  • motor to tongue from CN XII for all muscles except palatoglossus (CN X)
19
Q
A
20
Q

What is the blood supply to the hard palate?

A
  • Primary hard palate (anterior to incisive foramen)
    • nasopalatine
    • anterior and posteiror superior alveolar
  • Secondary hard palate
    • major: greater palatine
    • minor: nasopalatine, ant/post superior alveolar
21
Q

Which muscles contribute the most to velopharyngeal function?

A
  1. Levator veli palatini
  2. Musculus uvulus
  3. Superior pharyngeal constrictor
22
Q

Describe the innervation to muscles that contribute to the soft palate / velopharyngeal function

A
  • All muscles are innervated by the pharyngeal plexus CN X (CN IX): LVP, PP, PG, SPC, musculus uvulus EXCEPT:
  • TVP - by CN V
23
Q
A