Head And Neck Cancer Flashcards

1
Q

What viruses cause oro and naso pharynx cancer respectively

A

Hpv causes oral
EBV causes nasopharyngeal

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2
Q

Managment of erythromycin/leukoplakia

A

Requires urgent 2 week assessment for biopsy to exclude cancer

Regular monitoring

Reduce risk factors

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3
Q

Red flags for oral cavity cancer that require urgent referral

A

Unexplained ulceration in the mouth for more than 3 weeks

Lump on lip or in oral cavity

Erythroleukoplakia

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4
Q

Red flag referrals for laryngeal cancer

A

Over 45 with an unexplained neck lump or perisistent unexplained hoarseness

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5
Q

Referral criteria for 2ww in thyroid cancer

A

Anyone with an unexplained neck lump

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6
Q

Presentation of perisient ulcer,erythroleukoplakia, referred otalgia and cervical lymphadenopathy

A

Oral SCC

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7
Q

What is trotters syndrome suggestive of and what is the triad

A

Unilateral conductive hearing loss
Trigeminal neuralgia
Defective mobility of the soft palate

Suggestive of nasopharyngeal cancer

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8
Q

Features of nasopharyngeal cancer

A

Unilateral obstruction, polyp, bloody discharge, otalgia and trotters syndrome

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9
Q

Features of oro/hypopharyngeal cancer

A

Odyno/dysphagia, foreign body sensation, dysphasia, otalgia and cervical lymphadenopathy

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10
Q

Features of laryngeal cancer

A

Hoarseness of voice, stridor, dysphagia, referred otalgia and cervical lymphadenopathy

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11
Q

What is the main investigation that will occur for those with a 2ww for head and neck cancer

A

Flexible nasal endoscopy

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12
Q

What happens if a lesion is found in those having a flexible nasal endoscopy

A

Biopsy via:

Incisional biopsy
Fine needle aspirate (lymph)
Core bopsy

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13
Q

What imaging is used in HNSCC

A

MRI is the mainstay

CT neck and chest for metastasis

PET for unknown primary

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14
Q

Tx for HNSCC

A

Surgery is the mainstay with curative intent

Radiotherapy is used for early cancer

Chemo not really, used as adjuvant for locally advanced or metastatic disease

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15
Q

Acute side effects of radiotherapy to head and neck

A

Mucositis
Skin erythema
Loss of taste

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16
Q

Late side effects of HNSCC radiotherapy

A

Impaired healing
Osteoradionecrosis
Impaired swallow, speech and taste
Radiation induced tumours

17
Q

What drugs can cause mouth ulceration (CBL)

A

Nicorandil