Head and Neck Flashcards
What are micro-calcifications in a thyroid nodule most associated with?
Papillary thyroid carcinoma
Thyroid nodule MACROcalcification is most associated with?
Medullary thyroid cancer
Comet tail artifact is most commonly seen with what, in the neck?
Benign thyroid lesions typically colloid thyroid nodules
What are the features of Riedel thyroiditis?
Replacement of the thyroid gland with fibrous tissue.
Enlargement of the thyroid with compression of adjacent structures
What is Riedel thyroiditis associated with?
It is an IgG4 disease so associated with other IgG4 diseases.
- retroperitoneal fibrosis
- sclerosing cholangitis
- orbital pseudotumour
- Autoimmune pancreatitis
Where are thyroglossal duct cysts most commonly found?
Midline.
Infrahyoid 45%
At the hyoid 30%
Suprahyoid 25%
Most common location for ectopic thyroid?
Base of tongue - lingual thyroid.
What is the most common cause of hyperthyroidism?
Graves disease
Typical imaging features of Graves disease?
Enlarged thyroid.
Thyroid inferno pattern on colour Doppler.
Increased uptake on Tc99m Pertechnetate, and I-123
What is the most common cause of hypothyroidism and goitre?
Hashimotos thyroiditis
Classic findings of Hashimotos thyroiditis
Heterogeneous appearance - giraffe skin
Hyperechoic regenerative nodules
Low uptake of Tc99m
Diffuse uptake on PET
How does follicular thyroid cancer typically metastasize?
Haematogenous spread i.e. bone, lung
What is medullary thyroid cancer associated with?
MEN IIa and MEN IIb
How do thyroid lung mets typically present?
Miliary
Most common cause of primary hyperparathyroidism?
Parathyroid adenoma.
What is the most sensitive test to identify parathyroid adenoma?
4D CT I.e. triple phase.
Appear as oval lesions
Avidly enhances arterial phase more than thyroid.
Washes out on delayed phase more than thyroid
Tc99m Sestamibi scan
What is an esthesioneuroblastoma?
Tumour of the olfactory cells
What are the typical imaging appearances of an esthesioneuroblastoma?
Solid AVIDLY enhancing mass centered on the cribiform plate.
Dumbbell shaped and extends upwards into the brain.
Where do chordomas originate from?
Originate from the primitive notochord (earliest foetal axial skeleton).
They occur most typically in the sacrum and the clivus.
What are the imaging appearances for a chordoma?
Very high T2 signal.
Heterogeneous honeycomb enhancement.
How can you differentiate between a chondrosarcoma or a chordoma?
Chondrosarcoma are more lateral within the clivus.
Chordomas are within the midline.
What are juvenile nasopharyngeal angiofibromas?
Benign but locally aggressive, highly vascular tumours, centered on the sphenopalatine foramen.
Occurs most in teenagers with nosebleeds.
What is Osler-Weber-Rendu syndrome?
Hereditary haemorrhagic telangiectasia.
Autosomal dominant
Characterised by multiple AVMs
Where does Osler-Weber-Rendu syndrome typically occur?
Nasal 90%
Skin 90%
Liver 70-80%
What is the classical imaging appearances of an antrochoanal polyp?
Well defined mass in the maxillary sinus.
Widening of the maxillary ostium, WITHOUT bony destruction
What is an inverted papilloma and what are its classical MRI appearance?
Sinonasal tumour.
Cerebriform pattern on T2 and T1 (looks like brain)
Can have bony destruction.
Inverted papillomas undergo malignant transformation, what do they turn into?
SCC
What is a plunging ranula?
Sublingual mucous retention cyst that extends down into the submandibular space, crossing the mylohyoid muscle
What is the most common salivary gland tumor?
Pleomorphic adenoma
What are the common imaging features of a pleomorphic adenoma?
USS - hypoechoic, posterior acoustic enhancement
MRI - very T2 bright
Where are Warthin tumours commonly found?
Parotid gland. Can be bilateral in 15% of cases.
How can you tell the difference between Pleomorphic adenoma and Warthin tumours?
Warthin tumours shows uptake of Tc Pertechnetate.
What are the most common malignant tumours of the salivary glands?
1st. Mucoepidermoid carcinoma
2nd. Adenoid cystic carcinoma.
How do mucoepidermoid carcinoma and adenoid cystic carcinoma typically spread?
Perineural spread.
Require careful long term followup
Where do mucoepidermoid and adenoid cystic carcinoma typically affect?
Minor salivary glands - the small and unnamed salivary glandular tissue scattered throughout the oral cavity
Patient has bilateral lymphoma of the parotid glands. What underlying disease do they classically have?
Sjogrens disease.
What is a paraganglioma and what are its classical imaging appearances on MRI?
They are also called glomus tumours.
Neuroendocrine tumor.
Highly vascular, containing micro haemorrhages, causing salt and pepper appearance on MRI.
Masticator spaces malignancy/infection can spread to which other structures?
Cavernous sinus or orbital apex via the pterygopalatine fossa
What is the “danger space” of the head and neck?
Space anterior to the cervical spine (prevertebral deep cervical fascia) that extends from the skull base to the mediastinum
Necrotic retro pharyngeal lymph nodes suggest what pathology?
SCC metastatic nodal disease
Papillary thyroid carcinoma nodal disease
What is Grisel syndrome?
Retropharyngeal abscess causing:
- Torticollis
- Subluxation of the atlantoaxial joint.
What is Lemierre syndrome?
Jugular vein thrombosis and septic emboli from neck infection.
What 4 spaces surround the parapharyngeal space?
Anterior - masticator space
Lateral - parotid space
Posterior - carotid space
Medial - superficial mucosal space
Which tumour is classically found in the fossa of Rosenmuller, in typically Chinese patients?
Nasopharyngeal carcinoma
What is nasopharyngeal carcinoma typically associated with?
EBV
What Tulosa Hunt syndrome?
Orbtal pseudotumour (inflammation of the extra ocular muscles) also involving the cavernous sinus
What is the most common malignant orbital tumours in childhood?
Rhabdomyosarcoma
Retinoblastoma
Children with bilateral retinoblastomas are also at risk of which other tumours?
Trilateral renitoblastoma - Bilateral retinoblastoma and pineoblastoma
Quadrilateral retinoblastoma - Bilateral retinoblastoma, pineoblastoma, suprasella tumour.
Osteosarcoma
What is the classic triad of neuromyelitis optics?
Optic neuritis
Myelitis
Anti aquaporin 4 antibody
What order does thyroid eye affect the eye muscles?
IM SLO
Inferior
Medial
Superior
Lateral
Oblique
What are the orbital findings of a carotid cavernous fistula?
Pulsatile exophthalmos
Enlargement of the orbital veins
What is the most common cause of exophthalmos after a viral illness in children?
Orbital lymphangioma
Parotid lymphoma imaging features?
Multicystic appearance of both parotid glands.
Honeycomb appearance on MRI
Classic imaging appearance of HIV parotitis?
Multiple bilateral hypoechoic cysts without posterior acoustic enchantment
How do adenoid cystic carcinomas typically enhance?
Both high grade and low grade adenoid cystic carcinomas typically enhance homogenously.
What do cholesteatoma look like on MRI?
T1 low
T2 bright
Restricted diffusion
No enhancement
Most common primary intra ocular malignancy in adults?
Malignant uveal melanoma
High T1
Intermediate T2
Most common pathogen that results in retropharyngeal abscess
Staphylococcus aureus
Where are simple rannulas located?
Sublingual space
What is Gorlin Goltz syndrome?
Basal cell naevus syndrome
Multiple odontogenic keratocysts
BCCs
What does odontogenic keratocysts look like on CT and MR
Unilocular
Expansile
Typically posterior mandible
High T1 due to cholesterol and keratin
Heterogeneous T2
Restricted diffusion
How does Horner’s syndrome present?
- Enophthalmos
- Ptosis
- Miosis (small pupil)
What are causes of Horner’s syndrome?
Pancoast tumour
Carotid artery aneurysm/dissection
Caroticocavernous fistula
Transverse temporal bone fracture hearing loss type?
Sensorineural
Longitudinal temporal bone fracture hearing loss type?
Conductive due to involvement of ossicles
Mucocele Vs antrochoanal polyp?
Antrochoanal polyp widens the maxillary sinus ostium and can extend into the nasopharynx
Classic imaging appearance of ameloblastoma?
“Soap bubble” appearance
Resorption of adjacent teeth
Avidly enhancing papillary projections are common
Age group of capillary Vs cavernous hemangiomas of the orbit?
Capillary hemangioma - child
Cavernous hemangioma - adults
Typical appearance of a cricopharyngeal bar?
Posterior oesophageal indentation at C5-C6.
Most common intraconal vascular lesion?
Cavernous haemangioma
Cavernous hemangioma MRI appearance?
T1 - iso to muscle
T2 - hyperintense to muscle, dark capsule
Gd - slow irregular enhancement