HDV

Question 1

What viral family is HDV?

Answer 1

HDV belongs to the Deltavirus family…that’s really easy

Question 2

What kind of genome does HDV have?

Answer 2

-ssRNA…circular

Question 3

What is the outermost layer of HDV?

Answer 3

An envelope

Question 4

How is HDV transmitted?

Answer 4

Blood

Sexual contact

Question 5

What is required for packaging of HDV?

Answer 5

HBsAg…the person has to be infected with HBV as well

Question 6

What is the incubation period for HDV?

Answer 6

Long…2-24 weeks

Question 7

How is HDV diagnosed?

Answer 7

ELISA (Anti-HDV delta-antigen IgM)

RT-PCR

Question 8

How is an HDV infection treated?

Answer 8

By treating HBV infection

Question 9

Is there an HDV vaccine?

Answer 9

No…but there is an HBV vaccine that is just as effective

Question 10

How many people in the world are infected by HDV?

Answer 10

15million

Question 11

What percentage of fulminant hepatitis infections are caused in part by HDV?

Answer 11

40%

Question 12

What order of infection is most likely to cause lethal fulminant hepatitis?

Answer 12

Already having chronic HBV and then acquiring HDV