Hb - structure, synthesis and iron metabolism Flashcards

1
Q

What is haemoglobin?

A

An iron containing protein synthesised (in the adult) by the erythroblast precursors in the bone marrow that will give rise to the mature rbc

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2
Q

What is haemoglobin composed of?

A

-2 dissimilar pairs of polypeptide chains each of which encloses an iron containing porphyrin ring called haem

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3
Q

What si the function of haem and of globin?

A

Haem - essential for oxygen transport
Globin - serves to protect haem from oxidation, renders the molecule soluble and permits variation in oxygen affinity

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