Hazardous Drugs Flashcards
What is the purpose of USP <800>?
… to describe the practice and quality standards for handling hazardous drugs (HDs) to promote patient safety, worker safety, and environmental protection.
What is a “hazardous drug”?
A hazardous drug is any drug that will render the patient harm by hurting their healthy cells causing organ damage, secondary cancers, and rendering them infertile.
Where can you locate the list of hazardous drugs? what all information is given to you?
the NIOSH List of antineoplastic Drugs, it gives you the category, explanation of the dangers, and general rules/safety measures
how long does it take secondary cancers to develop?
2-10 years
What are three ways to be affected by antineoplastic drugs?
inhalation, transfer, absorption through the skin
what kind of room must hazardous drugs be compounded in? what are the air exchanges per minute? what air flow must the PEC have?
a negative pressure room so the hazardous air does not flow out into the ante room
- 30 air exchanges per hour and the PEC must have vertical air flow so it is not blowing on the worker
How high must the hazardous air vent be out of the roof?
10 feet out of the roof
how often must environmental testing be done?
every 6 months
how often do employees need to be tested? what 2 tests do they do?
They need to be tested every 6 months and they do a fingertip test and a media fill test
Do the staff need to sign any paperwork?
yes, they need to sign paperwork that says they have been properly trained and know what to do in emergency situations, that they know the risks, and how to protect themselves.
What do you have to do to products before they can be transferred?
we have to wipe them down and put them in a separate container before they can be transported. we also NEED to label them as a hazardous product
What is special about the garbing in hazardous compounding?
The compounders must wear two pairs of gloves and two pairs of booties. They can not reuse their chemo gowns and they must take the gloves and gowns off in the buffer room instead of the ante room. They also must wash their hands after they leave the buffer room.
what is an adsorbent compounding sheet?
this is an adsorbent sheet that goes in the designated compounding area
what is a hazardous spill kit?
this is an emergency kit that you must have in every place where chemo is! this includes the trucks it is transported in and everything
will chemo always escape while compounding?
yes! there is no way it wont no matter how good you are
what is a closed system transfer device?
this is a tool that mechanically prohibits the transfer of environmental contaminants into the system and the escape of the hazardous drug or vapor concentrations outside of the system. THEY SHOULD BE USED ALL OF THE TIME UNTIL INJECTION INTO THE PATIENT
does every hazardous drug need to be handled with all of this precaution?
no, this is why we need to be aware of what NIOSH says about the drug we are handling
what precautions must we use if the drug is labeled “antineoplastic” by NIOSH?
ALL OF THEM
what precautions must we use if the drug is labeled “active pharmaceutical ingredient (API)” by NIOSH?
ALL OF THEM
what precautions must we use if the drug is thought to have sufficient risk by the pharmacy?
ALL OF THEM