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MOD 2 > Hard metals > Flashcards

Hard metals Flashcards

1
Q

What causes fibrosis of the lungs?

A

Silica

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2
Q

What abuse drug causes respiratory depression + endocardidtis

A

Opiates

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3
Q

Mineral dusts (coal dust, silica, asbestos, beryllium) cause?

A

Pneumonconioses

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4
Q

What are 2 types of organic solvents and what do they cause?

A

Chloroform + carbon tetrachloride

CNS depression + coma

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5
Q

What does cadmidium posioning cause?

A

renal tubular damage + skeletal abnormalities associated with calcium loss

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6
Q

Chronic aspirin posioning causes?

A

Analgesic nephropathy, hearing problems

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7
Q

Radon gas is a form of?

A

Uranium

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8
Q

Nitrosamines + nitrosamides cause?

A

Gastric carcinoma

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9
Q

Acetaminophen poisoning causes?

A

Acute liver failure, centrilobular necrosis

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10
Q

What disease is from cadmium posioning?

A

Itai-Itai

Japan - osteoporosis + osteomalcia

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11
Q

What causes heart disease?

A

CO + lead

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12
Q

Asbestosis causes?

A

Mesothelioma

(ferrunginous bodies)

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13
Q

Tachycardia, HTN, and peripheral vasoconstriction are caused by?

A

Cocaine

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14
Q

Where is cadmium found?

A

plants = food

mining

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15
Q

Hyperpigmentation + hyperkeratosis

A

Arsenic

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16
Q

What causes chloracne (dermatitis)? Who got this after poisoning?

A

Dioxins + PCBs

Viktor Yushenko

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17
Q

What amount of radiation hits the brain and is 100% lethal?

A

>50 Sv

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18
Q

What outdoor pollutant causes decreased lung function + lung inflammation + decreased exercise capacity and is largely mediated by free radicals?

A

Ozone

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19
Q

What is the usual dosage for radiation? Causes hair loss, vomiting

A

2-10 Sv

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20
Q

Where is arsenic found?

A

Naturually in soil + water

21
Q

If you smoke + are on oral contraceptives what can you get?

A

hepatic adenoma (benign)

22
Q

Aflatoxin causes?

A

Hepatocellular carcinoma

23
Q

High animal fat + low fiber causes?

A

colon cancer

24
Q

What causes COPD?

25
Q

Which drug deposits in skin and causes blue/gray discoloration/rash?

A

Antibiotic minocycline

26
Q

Mercury causes what disease?

A

Minamata disease –> major CNS damage

27
Q

What causes leukemia?

28
Q

Male + female infertility/stillbirths are caused by?

29
Q

What positively correlates to breast cancer?

A

Total dietary fat

30
Q

Lichtenberg figures are from what?

A

Lightning strikes

31
Q

Vit. C + E + B carotenes + selenium =

A

Anti-carcinogenic from anti-oxidant properties

32
Q

What causes liver angiosarcoma?

A

Vinyl chloride

33
Q

Pet dander, fungi, molds are types of?

A

Bioaresols

34
Q

Mercury + lead + arsenic cause:

A

Peripheral neuropathies

35
Q

Why is sulfur dioxide more dangerous than ozone?

A

It combines w/ ozone + particulate matter (witches brew) and causes burning sensation in nose + throat and difficulty breathing.

SD is found inpower plants, paper mills

36
Q

Which outdoor pollutant causes increased respiratory symptoms + mortality in COPD patients and increased hospitalilations in asthma?

A

Sulfur Dioxide

37
Q

Malignant hyperthermia = what gene?

38
Q

What causes lung cancer?

A

Radon, asbestos, silica

39
Q

What constitues hypothermia?

A

Body temp less than 90

40
Q

Benzene posioning causes what?

A

Bone marrow aplasia –> acute myeloid leukemia

41
Q

What is the definition of particulate matter (soot)?

A

Fine or ultrafine particles less than 10 um in diameter.

42
Q

What bacteria virtually colonizes all burns?

A

Pseudomonas aeruginosa

43
Q

Pesticides like DDT + PCBs + dioxin do what?

A

Disrupt hormonal balance

44
Q

How do you get mercury posioning?

A

Fish or mercury vapors in dental amalgams?

45
Q

Ataxic gait + renal toxicity are caused by?

46
Q

Rash around eyes, nose, anus

Anorexia

A

Zinc deficiency

47
Q

Goiter and hypothyroidism

A

Iodine deficiency

MOD 2 (9 decks)

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