Hamidullah Flashcards

1
Q

Which of the following microorganism cause Lymphogranuloma venereum?

A) Haemophilus ducreyi

B) Chlamydia trachomatis

C) Neisseria gonore

D) Treponema pallidum

E) Bartonella henselae

A

B) Chlamydia trachomatis

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2
Q

Which of the following virulence factor of fungus defining an aggregate of microorganisms to adhere each other on a surface?

A) Dimorphism

B) The motolerability

C) Biofilm

D) Capsule

E) Enzyme production

A

C) Biofilm

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3
Q

Which of the following form is the cause of relapse in plasmodial infections?

A) trophozoite

B) gametocyte

C) schizont

D) tachysporozoite

E) bradysporozoite

A

E) bradysporozoite

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4
Q

Which of the following is the infective form of the malarial parasites?

A) Ookinete

B) Gametocyte

C) Sporozoite

D) Oocyst

E) Schizont

A

C) Sporozoite

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5
Q

Which of the following antifungal binds to microtubules and inhibits mitosis of a certain fungi?

A) Amphotericin B

B) Azoles

C) Griseofulvin

D) Allylamines

E) Echinocandins

A

C) Griseofulvin

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6
Q

52.Which of the following dimorphic fungi infections frequently acquired while visiting bat caves without airway protection?

A) Sporothrix schenckii

B) Coccidioides immitis

C) Blastomyces dermatitidis

D) Paracoccidioides brasiliensis

E) Histoplasma capsulatum

A

E) Histoplasma capsulatum

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7
Q

Which of the following blood paranite causes most severe form of malaria?

A) Plasmodium falciparum

B) Plasmodium vivar

C) Plasmodium ovale

D) Plasmodium malarian

E) Plasmodium knowlesi

A

A) Plasmodium falciparum

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8
Q

Bacteria become resistant to which antimicrobial agent by the metabolic bypass?

A) Aminoglycoside

B) Macrolide

C)Trimethoprim

D) Tetracycline

E) Chloramphenicol

A

C)Trimethoprim

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9
Q

Which of the following antibacterial agent damage to the plasma membrane, leads to leakage of the cell contents and ultimately death of the cell?

A) Sulfonamides

B) Carbapenems

C) Macrolides

D) Polymyxins

E) Vancomycin

A

D) Polymyxins

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10
Q

Bacteria become resistant to which antmacrobial agent by replacing the last D-alanine with D-lactate in pentapeptide chain?

A) Trimethoprim

B) Vancomycin

C) Tetracycline

D) penicillin

E) Aminoglycoside

A

B) Vancomycin

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11
Q

Which of the following antibacterial agent inhibit the nucleic acid synthesis?

A) Chloramphenicol

B) Penicillin

C)Fluoroquinelones

D)Tetracyclines

E) Chindamycin

A

C)Fluoroquinelones

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12
Q

Which of the following method can be use to determine the antimicrobial susceptibility by a plastic strip that contain antibiotic gradient?

A) Agar Dilution

B) Disc Diffusion

C) Micro Dilution

D) E-test (Strip gradient test)

E) Broth Dilution

A

D) E-test (Strip gradient test)

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13
Q

Which of the following method can be used to determine the Minimum Inhibitory Concentration(MIC) of antibiotics on test tubes that include different antibiotic concentration?

A) Agar dilution

B) Broth dilution

C) Micro dilution

D) E-test (Strip gradient test)

E) Disc diffusion

A

B) Broth dilution

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14
Q

Which of the following antifungal binds to fungal membrane sterols and alters permeability?

A) Griseofulvin

B) Echinocandins

C) Amphotericin B

D) Allylamines

E) Azoles

A

C) Amphotericin B

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15
Q

Which of the following antibacterial agent inhibit protein synthesis by binding to 50S subunit?

A)Vancomycince

B) Macrolides

C) Fluoroquinolones

D) Aminoglycosides

E) Carbapenems

A

B) Macrolides

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16
Q

Which of the following is false for Coxialla burnetii?

A) Survive for months due to endospore formation.

B) Transmitted by arthropods

C) Cause zoonotic disease

D) Causative agent of Q fever

E) Does NOT cause skin rash

A

B) Transmitted by arthropods

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17
Q

Which of the following antimicrobial resistance mechanism is composed by efflux pump that expels the antibiotic before it reaches its target?

A) Enzymatic inhibition

B) Decreased uptake

C) Increased export

D) Altered target

E) Metabolic bypass

A

C) Increased export

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18
Q

Which of the following antibacterial agent inhibit synthesis of essential metabolites?

A) Macrolides

B) Aminoglycosides

C)Tetracyclines

D) Trimethoprim

E) Clindamycin

A

D) Trimethoprim

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19
Q

Which of the following method drug-impregnated absorbent paper use to determine antimicrobial susceptibility testing?

A) Agar Dilution

B) Broth Dilution

C) Micro Dilution

D) E-test

E) Disc Diffusion

A

E) Disc Diffusion

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20
Q

Which of the following fungus produce a large capsul that protect microorganisms from the host attacks?

A) Penicillium marneffei

B) Paracoccidioides brasiliensis

C) Aspergillus niger

D) Sporothrix schenckii

E) Cryptococcus neoformans

A

E) Cryptococcus neoformans

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21
Q

Which of the following releases from ruptured erythrocyte and produces bouts of shivering fever (paroxysms) and sweating in Malarial infections?

A) ring form

B) gametocyte

C) merozoite

D) sporozoite

E) bradysporozoite

A

C) merozoite

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22
Q

Which of the following mechanism bacterial resistance genes are carried from one bacteria to another by bacteriophages?

A) Pilus

B) Transposon

C) Conjugation

D) Transformation

E) Transduction

A

E) Transduction

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23
Q

Which of the following method a solid medium use to determine the Minimum Inhibitory Concentration of an antibiotic?

A) Agar Dilution

B) E-test

C) Micro Dilution

D) Broth Dilution

E) Disc Diffusion

A

A) Agar Dilution

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24
Q

Which of the following Plasmodium species cause Quartian malaria?

A) Plasmodium falciparum

B) Plasmodium vivax

C) Plasmodium ovale

D) Plasmodium malariae

E) Plasmodium knowlesi

A

D) Plasmodium malariae

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25
Q

Which of the following define asexual life cycle of plasmodium?

A) schizont

B) sporogony

C) sporozoite

D) schizogony

E) tachysporozoite

A

D) schizogony

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26
Q

Which of the following dimorphic fungi find block like arthroconidia in free-living stage?

A) Paracoccidioides brasiliensis

B) Sporothrix schenckii

C) Blastomyces dermatitidis

D) Histoplasma capsulatum

E) Coccidioides immitis

A

E) Coccidioides immitis

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27
Q

Which of the following Chlamydia species also

known as TWAR agent?

A) C.trachomatis A, B, Ba, C

B) C trachomatis L1, L2, L3

C) C.trachomatis (D-K)

D) C.psittaci

E) C.pneumoniae

A

E) C.pneumoniae

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28
Q

Which of the following dimorphic fungi cause rose-gardener’s disease?

A) Parococcidioides brasiliensis

B) Penicillium marnefii

C) Histoplasma capsulatum

D) Sporothrix schenckii

E) Blastomyces dermatitidis

A

D) Sporothrix schenckii

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29
Q

Which of the following fungus produce a large capsul that protect microorganisms from the host attacks?

A) Penicillium marneffei

B) Paracoccidioides brasiliensis

C) Aspergillus niger

D) Sporothrix schenckii

E) Cryptococcus neoformans

A

E) Cryptococcus neoformans

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30
Q

The malaria parasite life cycle involves two hosts. Which of the following is the asexual life cycle of plasmodium?

a) Trophozoites
b) Merozoites
c) Schizogony
d) Sporogony
e) Sporozoites

A

c) Schizogony

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31
Q

In which of the following method a plate with wells use for to determine the Minimum Inhibitory Concentrations (MIC) of antibiotics?

a) Broth Dilution
b) Disc Diffusion
c) Micro Dilution
d) Strip gradient test
e) Agar Dilution

A

c) Micro Dilution

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32
Q

Which of the following survive for months due to endospore formation?

a) Chlamydia psittaci
b) Chlamydia pneumoniae
c) Coxiella burnetii
d) Rickettsia prowazekii
e) Rickettsia rickettsli

A

c) Coxiella burnetii

33
Q

Who as a garden hobby, which is may be the most risky fungal infection agent?

a) Piedra hotea
b) Malassezia furfur
c) Criyptocccus neoformans
d) Trichopyton rubrum
e) Sporothrix schenckii

A

e) Sporothrix schenckii

34
Q

Which of the following inhibit the cell wall synthesis?

a) Polymyxin
b) Chloramphenicol
c) Clindamycin
d) Macrolides
e) Vancomycin

A

e) Vancomycin

35
Q

Which of the following is not a dimorphic fungus?

a) Malassezia furfur
b) Penicillium marneffei
c) Paracoccidioides brasiliensis
d) Blastomyces dermatitidis
e) Histoplasma capsulatum

A

a) Malassezia furfur

36
Q

In which of the following mechanism bacterial resistance genes transfer by bacteriophages?

a) Transformation
b) Metabolic bypass
c) Conjugation
d) Transposon
e) Transduction

A

e) Transduction

37
Q

In which of the following bacterial resistance mechanism, membrane proteins expel the antibiotic from bacteria to the outside?

a) Efflux Pumps
b) Low affinity PBPS
c) Metabolic bypass
d) Transformation
e) R plasmids

A

a) Efflux Pumps

38
Q

Which of the following antimicrobial agent show its action on to the DNA of the bacteria?

a) Cephalosporins
b) Fluoroquinolones
c) Macrolides
d) Tetracyclines
e) Carbapenems

A

b) Fluoroquinolones

39
Q

Which of the following dimorphic fungal infection is commonly related to the inhalation of contaminated extracts of bats?

a) Histoplasma capsulatum
b) Penicillium marneffel
c) Coccidioides immitis
d) Blastomyces dermatitidis
e) Sporothrix schenckii

A

a) Histoplasma capsulatum

40
Q

The malaria parasite life cycle involves several stages. Which of the following is the infective form of the malarial parasites?

a) Merozoites
b) Sporozoites
c) Trophozoites
d) Schizont
e) Gametocyte

A

b) Sporozoites

41
Q

Which of the following is define accumulations of microorganisms aggregates on a surface?

a) Dimorphism
b) Capsule
c) Cell wall components
d) Enzyme production
e) Biofilm

A

e) Biofilm

42
Q

Which of the following method drug-impregnated absorbent paper use for antimicrobial susceptibility testing?

a) Broth Dilution
b) Disc Diffusion
c) Micro Dilution
d) Agar Dilution
e) Macro Diffusion

A

b) Disc Diffusion

43
Q

Which of the following antifungal drug inhibit the DNA synthesis of fungi?

a) Griseofulvin
b) Azoles
c) Amphotericin B
d) Flucytosine
e) Echinocandins

A

d) Flucytosine

44
Q

Which is not dimorphic fungi?

A

Candida albicans

45
Q

Frie testi hangi hastalığın tanısında kullanılır?

A

C.trachomatis L1,L2,L3

46
Q

Which drug inhibits synthesis of essential acids?

A

Sulfonamides

47
Q

Where is end of sexual cycle of malaria forms?

A

The gut of mosquito

48
Q

Transmitting resistance gene by pilus?

A-)Conjugation

B-)Transduction

C-)Transformation

A

A-)Conjugation

49
Q

True pathogenic fungal exhibit?

A-) distribute around worldwide

B-) very infective by respiratoy way

C-)Thermal dimorphic

D-)produce spore

E-)produce mycelium

A

C-)Thermal dimorphic

50
Q

Which drug could inhibit by beta lactamase enzyme?

A-)Vancomycin

B-)Cephalosporin

A

B-)Cephalosporin

51
Q

Kapsül oluşturan?

A

C.neoformans

52
Q

Which drug types inhibit synthesis of ergosteral enzyme?

A

Azoles

53
Q

Which infective form of Malaria enter human body?

A

Sporozoite

54
Q

Which of the following antibacterial agent shows its effect on metabolism of folic acid?

A) Vancomycin

B) Aminoglycosides

C) Fluoroquinolones

D) Beta Lactam Drugs

E) Sulphonamides

A

E) Sulphonamides

55
Q

Some species of Plasmodium are human-host specific Plasmodium species. Which of the following Plasmodium species can cause malaria in both human subjects and animals?

A) P. falciparum

B) P. ovale

C) P. knowlesi

D) All the above

E) None of the above

A

C) P. knowlesi

56
Q

Which of the following dimorphic fungi causes Lymphocutaneous infection when contaminated plant matter penetrates the skin?

A) Histoplasma capsulatum

B) Coccidioides immitis

C) Blastomyces dermelitials

D) Paracoccidioides brasiliensis

E) Sporothrix schencidi

A

E) Sporothrix schencidi

57
Q

Which of the following term is describing plasmids transferred via sex pili?

A) Bacteriophage

B) Transposon

C) Conjugation

D) Transformation

E) Transduction

A

C) Conjugation

58
Q

Which of the Plasmodium species gametocytes is “banana shaped”?

A) Plasmodium falciparum

B) Plasmodium vivax

C) Plasmodium ovala

D) Plasmodium malariae

E) Plasmodium krowlesi

A

A) Plasmodium falciparum

59
Q

Which of the following microorganism fever?

A) Rickettsia prowazekii

B) Rickettsia typhi

C) Bartonella henselae

D) Ehrlichia sennetsu

E) Coxiella burnetii

A

E) Coxiella burnetii

60
Q

Which of the following dimorphic causes “Rose gardener’s disease”?

A) Histoplasma capsulatum

B) Coccidioides immitis

C) Blastomyces dermatitidis

D) Paracoccidioides brasiliensis

E) Sporothrix schenckii

A

E) Sporothrix schenckii

61
Q

Which of the following antibacterial agent inhibit
the nucleic acid synthesis?

A) Chloramphenicol

B) Penicillins

C) Fluoroquinolones

D) Tetracyclines

E) Clindamycin

A

C) Fluoroquinolones

62
Q

Which of the following is the infective form of the plasmodial parasites?

A) Ookinete

B) Gametocyte

C) Sporozoite

D) Oocyst

E) Schizont

A

C) Sporozoite

63
Q

Which of the following does not inhibit the protein synthesis?

A) Aminoglycosides

B) Macrolides

C)Clindamycin

D) Fluoroquinolones

E) Tetracyclines

A

D) Fluoroquinolones

64
Q

Which of the following microorganism cause Recrudescent typhus (Brill-Zinsser disease)?

A) Coxiella bumetii

B) Rickettsia tsutsugamushi

C) Rickettsia typhi

D) Bartonella henselae

E) Rickettsia prowazekii

A

E) Rickettsia prowazekii

65
Q

Which of the following dimorphic fungi infections frequently acquired while visiting bat caves without airway protection?

A) Sporothrix schenckii

B) Coccidioides immitis

C) Blastomyces dermatitidis

D) Paracoccidioides brasiliensis

E) Histoplasma capsulatum

A

E) Histoplasma capsulatum

66
Q

Which of the following microorganism is causative agent of Q fever?

A) Rickettsia prowazekii

B) Rickettsia typhi

C) Ehrlichia sennetsu

D) Coxiella burnetii

E) Bartonella henselae

A

D) Coxiella burnetii

67
Q

Which of the following is not a dimorphic fungus?

a) Blastomyces dermatitidis
b) Penicillium marneffei
c) Aspergillus niger
d) Paracoccidioides brasiliensis
e) Histoplasma capsulatum

A

c) Aspergillus niger

68
Q

Protein Synthesis inhibition

A

Oxazolidinone

69
Q

Polyenes gurubundan olanı?

A

Amphotericin B

70
Q

inhibit the ergesterol synthesis

A
  • Allylamines
71
Q

inhibit the ergesterol synthesis

A

Allylamines

72
Q

which is the earlier stage of the malaria?

A

ring form

73
Q

B lactamase enzimi hangi sistemi kullanir?

A

enzyme inhibition

74
Q

macrospore ve microspore’un birleşip zigot oluşturduğu yer?

A

-stomach of mosquito

75
Q

Q Fever ile ilgili hangisi yanlıştır?

A-Hava yoluyla bulaşan bir hastalıktır

B-Causative agent sensitive to environmental condition

C- Causitive agent can not cause casisitive

D- Causetive agent is coxiella burnetti

E-Causetive agent is zoophilic.

A

B-Causative agent sensitive to environmental condition

76
Q

30s’e bağlanarak protein sentezini inhibe eden antimicrobial agent?

A-Sulfanomide

B-Tetracyclines

C-Macrolides

D-Carbapenem

E-….

A

B-Tetracyclines

77
Q

kümes hayvanlarından bulaşan ve atypic pneumonia etkeni nedir? chlamydia psittaci

A

chlamydia psittaci

78
Q

exoerythrocytic stage nerede olur?

A

Liver tissue of human body

79
Q

Which of the following plasmodium species can be distinguished from the others by the gametocyte form on a thin smear?

a) Plasmodium falciparum
b) Plasmodium malariae
c) Plasmodium vivax
d) Plasmodium ovale
e) Plasmodium knowlesi

A

a) Plasmodium falciparum