HALOGEN

Question 1

MOA: iodination of aromatic residues (phenylalanyl and tyrosyl) and oxidation of (sufhydryl groups)

Answer 1

Iodophors

Question 2

I2 + surfactants; reduces volatility and removes irritant properties

Answer 2

Iodophors

Question 3

Oldest and most effective germicide

Answer 3

Iodine

Question 4

2% I2 in H2O + NaI

Answer 4

Iodine Solution

Question 5

2% I2 in 50% ROH + NaI

Answer 5

Iodine tincture

Question 6

5% I2 in H20 + KI

Answer 6

Strong Iodine or Lugol’s Solution

Question 7

very water soluble, non toxic, non volatile, non staining, non irritating

Answer 7

Povidone-Iodine

Question 8

disinfection of water supplies

Answer 8

Chlorine

Question 9

active germicidal species formed when chlorine is dissolved in water

Answer 9

Hypochlorous acid HCIO

Question 10

MOA: chlorination of amide N and oxidation of SH-group

Answer 10

Chlorine

Question 11

2.5% chlorine + complex coagulant mixture

Answer 11

Chlor-Floc

Question 12

Clarifies the water of turbidity

Answer 12

Chlor-Floc

Question 13

uses water disinfection

Answer 13

Halazone

Question 14

N,N-Dichlorodicarbonamidine (Azochloramid)

Answer 14

Chloroazodin

Question 15

Use: wound solution, dental carries, lavage, irrigation
Long acting due to slow reaction w/ water

Answer 15

Chloroazodin

Question 16

Chlorpactin

Answer 16

Oxychlorosene sodium

Question 17

Combines the germicidal properties HOCl w/ emulsifying, wetting, and keratolytic actions of anionic detergent

Answer 17

Oxychlorosene sodium

Question 18

Use: rapid cidal action used to treat localized infections, remove necrotic tissues from massive infections

Answer 18

Oxychlorosene sodium

Question 19

aka Quaternary Ammonium Compounds

Answer 19

Cationic surfactants

Question 20

polar head and non polar hydrocarbon chain that form micelles

Answer 20

Cationic surfactants

Question 21

1935: pioneered quats as antimicrobials

Answer 21

Gerhard Domagk

Question 22

MOA: dissolution of surfactant into the microbial cell membrane, destabilization lysis

Answer 22

Cationic Surfactants

Question 23

Use: detergent, emulsifier, wetting agent, antiseptic w/ NaNo3 as preservatives

Answer 23

Benzalkonium chloride

Question 24

Zephiran

Answer 24

Benzalkonium chloride

Question 25

Diaprene

Answer 25

Methylbenzethonium chloride

Question 26

for diaper rush in infants caused by Candida albicans

Answer 26

Diaparene

Question 27

Phemerol

Answer 27

Bezethonium chloride

Question 28

Cepacol
Uses: antiseptic for intact skin and minor lacerations

Answer 28

Cetylpyridinium chloride

Question 29

Uses: skin antisepsis and irrigation of mucous membranes

Answer 29

(Phemerol) Benzethonium chloride

Question 30

As mouthwash and throat lozenges

Answer 30

Cetylpyridinium chloride