BIGUANIDES, DYES, HEAVY METALS, PRESERVATIVES Flashcards

1
Q

Alexidine, Chlorhexidine, Hexitidine

A

Biguanides

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2
Q

broad spectrum antibacterial but not effective against acid fast, spores and virus

A

Biguanides

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3
Q

Hibiclens, Orahex, GynePro

A

Chlorhexidine gluconate

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4
Q

originally tested as antimalarial

A

Chlorhexidine gluconate

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5
Q

antifungal (vaginal)
anthelmintic (oral)

A

Gentian Violet

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6
Q

antifungal for ringworm and athlete’s foot

A

Basic Fuchsin

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7
Q

weak antiseptic for cystitis and urethritis

A

Methylene Blue

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8
Q

inhibition/killing of microorganisms by using of very small amount of a chemical substance

A

Oligodynamic action

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9
Q

MOA: combination of metal ions with -SH groups

A

Oligodynamic action

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10
Q

Use: antiseptic, preservative, diuretic
MOA: covalent bond with -SH group

A

Mercury

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11
Q

Toxicity of Mercury

A

Minamata Disease (ataxia, muscle weakness numbness, narrowing field of vision)

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12
Q

Use: 1% soln as ophthalmic antiseptic, antibacterial for burns

A

Silver

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13
Q

Silver toxicity

A

Argyria (treatment NaCl)

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14
Q

prevention of neonatal conjunctivitis

A

2% aqueous soln of silver nitrate

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15
Q

Treatment of opthalmia neonatorum

A

Silver (Argyrol, Collarhol, Protargol, Silver sulfadiazine)

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16
Q

Use: prevention of algae in pools and fish tank
Application: meat products

A

Copper

17
Q

Toxicity of Copper

A

Wilson’s disease (Tx Penicillamine)

18
Q

Tx for dandruff (anti fungal)

A

Selenium

19
Q

metal that is antiseptic mouthwash

A

Zinc

20
Q

Preservatives in:
Cosmetics
Bread
Acidic preparations

A

Parabens
Calcium propionate
Sorbic and Benzoic acid

21
Q

MOA: metabolic inhibition in fungal cells

A

Organic acids

22
Q

MOA: inhibition of certain iron-containing enzymes of anaerobes

A

Nitrates, Nitrites

23
Q

Use: Prevent growth C. botulinum in food and imparts a red color

A

Nitrates and Nitrites

24
Q

Salitre

A

Potassium nitrate

25
Q

Potassium nitrate + hemoglobin=

A

pinkish color on meat products

26
Q

-anti fungal
-low toxicity due to rapid hydrolysis in vivo
-preservative for liquid DF

A

P-hydroxybenzoic acid derivatives

27
Q

methylparaben, propylparaben, butylparaben, ethylparaben

A

P-hydroxybenzoic acid derivatives