hair Flashcards
Steel wool hair
Menke’s Kinky Hair
Menke’s Kinky Hair #1 hair abn
others
Pili torti,
T. nodosa and monilethrix
XLR, ATP7A- Cu2+ translocating membrane ATPase
Menke’s Kinky Hair
MKH
Bjornstad syndrome
Crandall’s syndrome, Citrullinemia
Bazex Follicular Atrophoderma
Pili Torti (Twisted hairs)
XLD
Hypotrichosis, hypohidrosis
Multiple BCCs
Bazex Follicular Atrophoderma
MR, seizures, cupids bow lips
Menke’s Kinky Hair
P. torti with deafness
• Bjornstad syndrome
• Crandall’s syndrome
– P. tori with deafness and hypogonadism
Two frayed ends like brooms ends
Trichorrhexis Nodosa
Argininosuccinic aciduria
Citrullinemia
MKH, Trichothiodystrophy, Netherton’s
Congenital Trichorrhexis Nodosa
- No argininosuccinase
- Acidosis
- MR
- Hair fluoresces red
Argininosuccinic aciduria
- No argininosuccinic acid synthetas
- Perioral and anal dermatitis
- P. torti as well
Citrullinemia
MKH, Trichothiodystrophy, Netherton’s
Congenital Trichorrhexis Nodosa
Bamboo or ball-in-socket
Trichorrhexis Invaginata
Clean break
Trichoschisis
– Trichothiodystrophy or PIBIDS hair abnormalities
Trichoschisis -Congenital
Trichorrhexus nodosa
• Netherton’s
– Icthyosis linearis circumflexa
– Atopy
-T. nodosa
Trichorrhexis Invaginata
hair abn in Netherton’s
T. nodosa
Trichorrhexis Invaginata
• Elliptical nodes that breaks at the nodes
Monilethrix
– Short, brittle hair
– KP
– MR
– Nail and teeth defects
Monilethrix
• Tiger-tail hair with alternating dark and light with NORMAL light (not polarized)
– Due to air spaces
Pili Annulati
• Damage causing split ends
Trichoptilosis
• Retention and desquamation of IRS
• Slides along shaft
vs nits
– Hair Casts
Nits do not slide
- Triangular hair shaft with central groove
* Uncombable hair that is like spun glass
Pili trianguli et canaliculi
Plakoglobin defect
• Woolly hair, PPK, cardiomyopathy
Naxos Disease
Naxos Disease inheritance
• AR
- AR
* DNA helicase gene RECQL4
Rothmund-Thomson
- Sparse hair
- Poikiloderma
- Cataracts
- Hypogonadism
- SCC, BCC and others
Rothmund-Thomson
- Light, fine hair
- Sweating abnormal
- Teeth and nail abnormalities
- Frontal bossing
Anhidrotic Ectodermal Dysplasia
- XLR
* Ectodysplasin A
Anhidrotic Ectodermal Dysplasia
- AD
- Connexin 30
- Hair loss, PPK, nails
Hidrotic Ectodermal Dysplasia
• T. effluvium
___ w after event anagen → telogen
___m later shedding occurs
– Three to five weeks
– Two to three months
– Arrest of cell division
• Radiation, chemo, poisoning
• A. effluvium
– Young girls
– Blonde
– Anagen (ruffled cuticle) on pull test
• Loose anagen
Ophiasis
• Peripheral loss
____prognosis than patchy disease
• Worse
– Congenital or during childhood
– Temporal areas
• Complete loss or only vellus growth
• Triangular
– Increased catagen on bx
• Trichotillomania
– Pigment on bx
– Trichomalacia
– Isolated patch
– 50% associated with a nevus
– Eye abnormalities
• Woolly Hair Nevus
– Post-puberty male
– Gradual curling and darkening androgenetic alopecia
Acquired Progressive Kinking
– AIDS and retinoids are etiologies
Acquired Progressive Kinking
– AR
– Hairless gene
• Papular atrichia
– Alopecia after birth
– Cysts on face and neck
– Few follicles present
• Papular atrichia
Vertex of black females
May be related to styling practices
Follicular degeneration (central centrifugal scarring alopeca)
– Premature loss of IRS with fibrosis
(central centrifugal scarring alopecia)
– Perifollicular erythema
– LP-like changes with scarring around follicle
• LPP