Haemostasis, Thrombosis and monitoring Flashcards
1
Q
risk factors for thrombosis
A
obesity immobility age lower limb surgery factor V Lieden malignancy pregnancy primary polycythemia (not secondary) peurperium antiphospholipid antibodies
2
Q
diagnosis of thrombosis
A
usually ultrasound, look for clot in vein and decreased compressibility
3
Q
3 types of antiphospholipid antibodies
A
lupus inhibitor (can prolong APTT)
anti-cardiolipin
anti-betaglycoprotein
4
Q
if you wanted to investigate an underlying thrombophilia what tests would you order?
A
FBE (maybe polycythemic) APTT/INR Factor V Ledien (use activated protein c resistance test) protein c, s, antithrombin anti-phospholipid antibodies
5
Q
monitoring of heparin
A
APTT
6
Q
monitoring of LMW heparin
A
anti-factor Xa test
7
Q
monitoring of warfarin
A
INR