Haemostasis, Thrombosis and monitoring Flashcards

1
Q

risk factors for thrombosis

A
obesity
immobility
age
lower limb surgery
factor V Lieden
malignancy
pregnancy
primary polycythemia (not secondary)
peurperium
antiphospholipid antibodies
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2
Q

diagnosis of thrombosis

A

usually ultrasound, look for clot in vein and decreased compressibility

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3
Q

3 types of antiphospholipid antibodies

A

lupus inhibitor (can prolong APTT)
anti-cardiolipin
anti-betaglycoprotein

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4
Q

if you wanted to investigate an underlying thrombophilia what tests would you order?

A
FBE (maybe polycythemic)
APTT/INR
Factor V Ledien (use activated protein c resistance test)
protein c, s, antithrombin
anti-phospholipid antibodies
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5
Q

monitoring of heparin

A

APTT

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6
Q

monitoring of LMW heparin

A

anti-factor Xa test

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7
Q

monitoring of warfarin

A

INR

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