Haemostasis Flashcards
Define haemostasis
Arrest or stoppage of bleeding
Initiation of haemostasis
Injury of blood vessel
3 stages
1,vasoconstriction
2,formation of platelet plug
3,coagulation of blood
Injury of the blood vessel is followed by
Damage of endothelium
Adherence of platelets to the exposed collagen is accelerated by
Von willbrand factor
ADP and thromboxane A2 are secreted by
Platelets attached to collagen during coating
Platelet plug or temporary plug is formed by
Aggregation of platelets
Platelet aggregation accelerated by
PAF (platelet activating factor)
Which blocks the ruptered part of blood vessel and prevent further blood loss
Fibrin thread attached to platelet plug
Vasoconstriction occurred by
Secretion of serotonin
Formation of prothrombin activator finally leads to
Blood clotting