haemoglobin - myoglobin

Question 1

define haemoglobin

Answer 1

responsible for transport of O2 throughout body

lower affinity to O2

forms sigmoid curve due to cooperative binding

has 4 Fe2+ atoms to bind 4 O2 molecules

Question 2

define myoglobin

Answer 2

stores and facilitates diffusion of O2 to muscles

higher affinity to O2

produces hyperbolic curve

1 Fe2+ atom to one O2 molecule

Question 3

what is the bohr effect?

Answer 3

Binding of H+ and CO2 lowers the affinity of haemoglobin for O2

ensures the delivery of O2 is coupled to demand

Question 4

what factors shift the haemoglobin curve to the left?

Answer 4

increased HbF

increased CO

Question 5

what factors shift the haemoglobin curve to the right?

Answer 5

decrease in pH

increase in Temp or pCO2