Haemoglobin

Question 1

Fn?

Answer 1

Absorbs O2 from lungs by forming oxyhaemoglobin;

Hb-H20 + O2 <=> Hb-O2 + H2O

Question 2

How does it carry out its fn?

Answer 2

O2 molecule replaces water molecules;

Forms reversible dative bond w Fe2+;

Oxyhaemoglobin carries O2 through oo from one part of body to another

Question 3

Why CO is a more poisonous?

Answer 3

CO is a stronger ligand than O2;

Form irreversible dative bonds w Fe2+ in haemoglobin; which is stronger;

CO displaces O2 in oxyhaemoglobin to form carboxyhaemoglobin

Hb-O2 + CO -> Hb-CO + O2

Cuts down O2 supply to body;

Accounting for toxic nature of CO;

=> O2 no this ability

Question 4

How is treatment with pure O2 effective?

Answer 4

Hb-O2 + CO -> Hb-CO +O2

[O2] increases, poe shifts to left;

=> forces CO off the haemoglobin