Haemoflagellates (trypanosomiasis, leishmaniasis) Flashcards
Describe the disease, vector and organism involved in the 3 main haemoflagellate associated diseases
- Chagas’s disease, vector - reduvid bug (triatomine), organism - Trypanosoma cruzi
- Human African trypanosomiasis AKA Sleeping Sickness, vector - tsetse fly, organism - Trypanosoma brucei
- Leishmaniasis, vector - sandfly, organism - leishmania spp.
Which vector and organism is responsible for causing Human African Trypanosomiasis (HAT) AKA Sleeping Sickness
Vector - tsetse fly
Organism - T.brucei
Which vector and organism is responsible for causing American trypanosomiasis ie. Chaga’s Disease
Vector - reduviid bug
Organism - T.cruzi
What vector is responsible for causing Leishmaniasis
Sandfly
What are the hotspots for visceral leishmaniasis
Bangladesh, Brazil, India, Nepal and Sudan
What are the hot spots for mucocutaneous leishmaniasis
Bolivia, Brazil, Peru
What are the hot spots for cutaneous leishmaniasis
Afghanistan, Brazil, Peru, Saudi Arabia, Syria
What type of leishmaniasis does this gentleman have and what is the prognosis/treatment?
Mucocutaneous leishmaniasis.
Begins with a skin ulcer that heals but after months/years, chronic ulcers appear on skin, mouth and nose leading to tissue destruction. Can be fatal if left untreated.
Treatment -
What type of leishmaniasis is this
Diffuse cutaneous leishmaniasis
What is the main foci of visceral leishmaniasis
Bihar, India
Which form of leishmania is injected into bloodstream by macrophages
Promastigote.
Transforms into amastigotes once phagocytise dby macrophages, where they multiply and are taken up by the sandfly again. Then transform into promastigotes in midgut of sandfly.
Describe prevention methods for leishmaniasis
NO vaccine.
Which country do you have both t.b. gambiense and t.b.rhodesiense
Uganda
Which leishmaniasis species causes post kalazar dermal leishmaniasis
L.donovani
