HAEMOFLAGELLATES Flashcards

1
Q

CA OF CHAGAS DISEASE

A

TRYPONASOMA CRUZI

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2
Q

CA OF AMERICAN TRYPANOSOMIASIS

A

TRYPANOSOMA CRUZI

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3
Q

VECTOR OF T. CRUZI

A

REDUVIID BUGS

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4
Q

VECTOR OF T. BRUCEI

A

TSETSE FLY

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5
Q

VECTOR OF LEISHMANIA SPP.

A

SANDFLY

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6
Q

IS OF T. CRUZI

A

METACYCLIC TRYPOMASTIGOTES

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7
Q

ZOONOTIC MAMMALIAN RESEVOIR HOST OF T. CRUZI

A

ARMADILLOS, MARSUPIALS, RACCOONS, RODENTS, & SOME OTHER PRIMATES

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8
Q

4 STAGES OF DEVELOPMENT OF T. CRUZI

A

AMASTIGOTE
PROMASTIGOTE
EPIMASTIGOTE
TRYPOMASTIGOTE

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9
Q

AMASTIGOTE, PROMASTIGOTE, EPIMASTIGOTE DEVELOPS IN THE ___ OF VECTORS

A

MIDGUT

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10
Q

WHERE DOES THE METACYCLIC TRYPOMASTIGOTE DEVELOP

A

HINDGUT

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11
Q

MORPHOLOGY OF TRYPOMASTIGOTE

A

C SHAPED/ U OR S SHAPED WITH PROMINENT KINETOPLAST

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12
Q

DIAGNOSTIC STAGE OF T. CRUZI

A

AMASTIGOTE

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13
Q

FURUNCLE LIKE LESIONS ASS. WITH IDURATION, CENTRAL EDEMA & REGIONAL LYMPHADENOPATHY

A

CHAGOMAS

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14
Q

PAINLESS BIPALPEBRAL EDEMA & CONJUNCTIVITIS

A

ROMAÑA’S SIGN

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15
Q

PRIMARY ORGAN AFFECTED IN CHRONIC PHASE OF T. CRUZI

A

HEART

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16
Q

ACUTE PASE TX OF CHAGAS DISEASE

A

NIFURTIMOX

BENZNIDAZOLE

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17
Q

SIDE EFFECT OF NIFURTIMOX

A

WEIGHT LOSS, ANOREXIA, BEHAVIORAL CHANGES & ANTABUSE EFFECT

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18
Q

SIDE EFFECT OF BENZNIDAZOLE

A

RASHES, BONE MARROW SUPPRESION, PERIPHERAL NEUROPHATY

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19
Q

CA OF HUMAN AFRICAN TRYPONASOMIASIS

A

TRYPANOSOMA BRUCEI

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20
Q

CA OF AFRICAN SLEEPING DISEASE

A

TRYPANOSOMA BRUCEI

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21
Q

3RD SUBSPECIES OF T. BRUCEI

A

TRYPANOSOMA BRUCEI BRUCEI

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22
Q

T. BRUCEI BRUCEI PRIMARILY AFFECT

A

WILD & DOMESTIC ANIMALS

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23
Q

T. BRUCEI GAMBIENSE IS RESPONSIBLE FOR WHAT TYPE OF SLEEPING SICKNESS

A

CHRONIC SLEEPING SICKNESS–95%

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24
Q

RESPONSIBLE FOR ACUTE SLEEPING SICKNESS– 5%

A

T. BRUCEI RHODESIENSE

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25
Q

PRIMARY ZOONOSIS OF T. BRUCEI RHODISIENSE

A

CATTLE & WILD ANIMALS

26
Q

RESERVOIR HOST OF T. BRUCEI GAMBIENSE

A

DOGS, PIGS, SHEEP

27
Q

IS OF T. BRUCEI

A

METACYCLIC TRYPOMASTIGOTE

28
Q

EARLY PHASE OF HAT

A

HEMOLYMPHATIC STAGE

29
Q

POSTERIOR CERVICAL LN ENLARGED, NON-TENDER & HAS RUBBERY CONSISTENCY

A

WINTERBOTTOM’S SIGN

30
Q

TRYPANOSOMAL CHANCRE IS MORE COMMON IN

A

GAMBIAN/CHRONIC SLEEPING SICKNESS

31
Q

LATE STAGE OF HAT

A

MENINGOENCAPHALITIC STAGE

32
Q

IT IS A DEEP DELAYED HYPERESTHESIA (BILATERAL PAIN OUT OF PROPORTION TO TISSUE INJURY)

A

KERANDEL’S SIGN

33
Q

CONTINUOUS CHANGES IN THE SURFACE COAT WHEREIN GLYCOPROTEINS HOST’S ANTIBODIES CANNOT RECOGNIZE THE PARASITE

A

ANTIGENIC VARIATION

34
Q

TX FOR EARLY STAGE

A

IV SURAMIN SODIUM- BOTH

IV PENTAMIDINE- GAMBIAN

35
Q

ARSENIC CONTAINING DRUGS CAUSES

A

FATAL ARSENIC ENCEPHALOPATHY

36
Q

HOW DO THE ARSENIC CONTAINING DRUG PREVENTED IN CAUSING FATAL ARSENIC ENCEPHALOPATHY

A

CO-ADMIN OF CORTICOSTEROIDS

37
Q

IT IS A FEBRILE EPISODE DUE TO TRYPANOSOME LYSIS AFTER MELARSOPROL TX

A

JARISCH- HERXHEIMER RXN

38
Q

2ND LINE OF TX. IF MELARSOPROL FAILED

A

NITROFURAZONE

39
Q

NEWER DRUG IN TX. OF HAT THAT IS LESS TOXIC & IS ALSO USED IN EARLY STAGE

A

ELFORNITHINE ( EFFECTIVE ONLY FOR T. BRUCEI GAMBIENSE)

40
Q

KNOWN AS DELHI BOIL BY CUNNINGHAM

A

LEISHMANIA SPP.

41
Q

ARTHROPOD VECTOR OF OLD WORLD LEISHMANIA

A

SANDFLY GENERA PHLEBOTOMIS

42
Q

ARTHROPOD VECTOR OF NEW WORLD LEISHMANIA

A

LUTZOMYIA

43
Q

PRIMARY RESERVOIR IN URBAN AREAS OF LEISHMANIA

A

DOGS

44
Q

PRIMARY RESERVOIR IN URBAN & RURAL AREAS OF LEISHMANIA

A

RODENTS

45
Q

IS OF LEISHMANIA

A

PROMASTIGOTE

46
Q

4 CATEGORIES OF LEISHMANIASIS

A

CUTANEOUS LEISHMANIASIS
DIFFUSE CUTANEOUS LEISHMANIASIS
MUCOCUTANEOUS LEISHMANIASIS
VISCERAL LEISHMANIASIS

47
Q

CUTANEOUS LEISHMANIAS IS COMPARED TO WHAT LEPROSY

A

TUBERCOID LEPROSY

48
Q

IT IS THE MOST COMMON LEISHMANIASIS

A

CUTANEOUS LEISHMANIASIS

49
Q

IT IS A ERYTHEMATOUS PAPULE OR NODULE AT THE INOCULATION SITE

A

ORIENTAL BUTTON

50
Q

DIFFUSE CUTANEOUS LEISHMANIASIS AKA

A

ANERGIC OR LEPRAMATOUS LEISHMANIAISIS

51
Q

IT MAY BE INITIALLY DIAGNOSED AS LEPRAMATOUS LEPROSY & HAS A LOCALIZED, NON-ULCERATING PAPULE

A

DIFFUSE CUTANEOUS LEISHMANIASIS

52
Q

IT IS A DISFIGURATION INVOLVEMENT OF MUCOUS MEMBRANES OF NASAL & ORAL CAVITIES/ NASAL SEPTUM DESTRUCTION

A

ESPUNDIA

53
Q

ESPUNDIA IS A CHARACTERISTIC OF

A

MUCOCUTANEOUS LEISHMANIASIS

54
Q

VISCERAL LEISHMANIASIS IS AKA

A

KALA AZAR

55
Q

ACUTE PHASE OF VL/KALA AZAR

A

2X DAILY FEVER SPIKES (DOUBLE QUOTIDIAN) W/ CHILLS

*MISTAKEN FOR MALARIA

56
Q

PHASE OF VL WITH S/S OF FEVER, WEAKNESS, LOSS OF APPETITE, WEIGHT LOSS, HEPATOSPLENOMEGALY

A

SUBACUTE & CHRONIC COURSE

57
Q

IN LEISHMANIA SKIN TEST/MONTENEGRO SKIN TEST, THE ONLY POSITIVE IS

A

CL & MCL

NEGATIVE FOR DCL & VL

58
Q

PRIMARY TX. OF LEISHMANIASIS

A

BASED ON ANTIMONY COMPOUNDS

59
Q

2ND DRUG OF CHOICE FOR LEISHMANIASIS

A

IV AMPHOTERICIN B

60
Q

LEISHMANIA IS DIVIDED INTO 2 WORLDS, WHAT ARE THE SPECIES IN OLD WORLD

A

L. TROPICA
L. AETHIOPICA
L. MAJOR

61
Q

SPECIES IN NEW WORLD

A
L. MEXICANA
L. AMAZONENSIS
L. GUYANENSIS
L. BRAZILENSIS
L. CHAGASI