AMOEBA Flashcards

1
Q

MOST INVASIVE AND ONLY THAT CAUSED COLITIS AND LIVER ABSCESS

A

ENTAMOEBA HISTOLYTICA

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2
Q

IS STAGE OF E. HISTOLYTICA

A

CYST

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3
Q

DEFINITIVE HOST OF E. HISTOLYTICA

A

HUMANS *NO ANIMAL RESERVOIR

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4
Q

STAGE IN E. HISTOLYTICA THAT CAUSES AMOEBIASIS

A

TROPHOZOITE

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5
Q

VIRULENCE FACTORS CAUSED BY E. HISTOLYTICA

A

ADHERENCE
INVASION
ENDOTOXINS

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6
Q

2 TYPES OF AMOEBIASIS FOR SYMPTOMATIC PX.

A

ACUTE DYSENTERIC & CHRONIC NON-DYSENTERIC

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7
Q

EXTRA-INTESTINAL AMOEBIASIS

A

AMOEBIC LIVER ABSCESS (ALA)

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8
Q

DIAGNOSIS OF ALA

A

ANCHOVY PASTE– ASPIRATION OF NON-ODOROUSM REDDISH BROWN

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9
Q

IN DX., TROPHOZOITE & CYSTS CAN BE SEEN IN WHAT?

A

TROPHOZOITE- LOOSE STOOL

CYST- SOLID STOOL

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10
Q

TREATMENT FOR INVASIVE FORM OF AMOEBIASIS

A

METRONIDAZOLE

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11
Q

TREATMENT FOR LUMINAL FORMS OF E. HISTOLYITICA

A

IODOQUINOFONUM, PAROMOMYCIN, DILOXANIDE

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12
Q

TX FOR EXTRAINTESTINAL AMOEBIASIS

A

METRONIDAZOLE + LUMINAL FORM DRUGS

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13
Q

COMMENSAL AMOEBAS (NON-INVASIVE)

A
E. DISPAR
E. MOSHKOVSKII
E. HARTMANI
E. COLI
E. POLECKI
E. CHATTONI
E. GINGIVALIS
ENDOLIMAX NANA
IODAMOEBA BUTSCHII
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14
Q

COMMENSAL AMOEBA THAT DOES’NT HAVE CYSTIC STAGE

A

E. GINGIVALIS

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15
Q

AMOEBA THAT IS TRANSMITTED THRU KISSING AND IS FOUND IN MOUTH

A

E. GINGIVALIS

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16
Q

MORPHOLOGICALLY SIMILAR TO E. HISTOLYTICA BUT HAVE DIFFERENT DNA & rRNA

A

E. DISPAR

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17
Q

PHYSIOLOGIC DISTINGUISHING CHARACTERISTIC OF E. MOSHKOVSKII

A

(ISOLATE) OSMOTOLERANT (CAN GROW AT ROOM TEMP, SURVIVE AT 0-40ºC)

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18
Q

DETECTED IN SEWAGES AND INDISTINGUISHABLE FR. E. DISPAR & E. HISTOLYTICA MORPHOLOGICALLY

A

E. MOSHKOVSKII

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19
Q

CHARACTERISTIC OF E. HARTMANI

A

DOES NOT INGEST RBC

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20
Q

MORPHOLOGY OF E. HARTMANI

A

SIMILAR TO E. HISTOLYICA BUT SMALLER

CYST: QUADRINUCLEATED; ROD-SHAPED

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21
Q

MORPHOLOGY OF E. COLI

A

LARGER TROPHOZOITE

CYST: DIFFERENTIATED FR. E. HISTOLYTICA
MORE GRANULAR CYTOPLASM
MORE NUCLEI (8)
SPHINCTER LIKE CHROMATOIDAL BODIES

22
Q

IT IS THE MORE COMMON AMOEBA

A

E. COLI

23
Q

FOUND IN INTESTINE OF PIGS & MONKEYS

A

E. POLECKI

24
Q

E. CHATTONI IS FOUND IN WHERE

A

MONKEYS & APES

25
Q

IT HAS THE SAME FREQUENCY AS TO E. COLI

A

ENDOLIMAX NANA

26
Q

MOTILITY OF E. POLECKI & E. CHATTONI

A

SLUGGISH MOTILITY

27
Q

COMMENSAL AMOEBA THAT IS UNINUCLEATED WITH LARGE GLYCOGEN BODY THAT STAINS DARK BROWN WITH IODINE

A

IODAMOEBA BUSHKII

28
Q

CAUSATIVE AGENT OF ACANTHOEMABA KERATITIS & GRANULOMATOUS AMEBIC ENCEPHALITIS

A

ACANTHAMOEBA SPP.

29
Q

CA OF PAM (PRIMARY AMOEBIC MENINGOENCEPHALITIS)

A

NAEGLERIA FOWLERI

30
Q

INFECTIVE STAGE OF ACANTHAMOEBA SPP.

A

TROPHOZOITE

31
Q

STAGES OF ACANTHAMOEBA

A

CYST & TROPHOZOITES

* NO FLAGELLATED STAGE

32
Q

ACANTHAMOEBA HABITAT

A

CAN SURVIVE IN CONTACT LENSES CLEANING SOLUTIONS

33
Q

HOW DO ACANTHAMOEBA REPRODUCE

A

BINARY FISSION

34
Q

HOW DO THE TROPHOZOITE STAGE OF ACANTHAMOEBA REPLICATE

A

BY MITOSIS (NUCLEAR MEMBRANE DOES NOT REMAIN INTACT)

35
Q

MORPHOLOGY OF TROPHOZOITE OF ACANTHOMEBA

A

ACTIVE W/ PROMINENT THORN-LIKE APPENDAGES – “ACANTHOPODIA”

36
Q

WHERE DOES THE TROPHOZOITE STAGE OF ACANTHAMOBA FEEDS

A

FEEDS ON GRAM-NEGATIVE BACTERIA, BLUE-GREEN ALGAE YEASTS

37
Q

MOST AFFECTED AREAS OF THE BRAIN IN GAE

A

POSTERIOR FOSSA STRUCTURES
THALAMUS
BRAINSTEM

38
Q

MAJOR DIFFERENTIAL TO BE RULED OUT IN DX AK

A

FUNGAL & HEPATIC KERATITIS

39
Q

DX. OF AK

A

EPITHELIAL BIPSY WITH CORNEAL SCRAPING

40
Q

DX OF GAE

A

USUALLY POSTMORTEM

41
Q

SPECIES TO HAVE CAUSED AK

A
A. CASTELLANI
A. CULBERTSONI
A. HUTCHETTI
A. POLYPHAGA
A. RHYSOIDES
42
Q

ONLY CURATIVE TX FOR AK & GAE

A

SURGICAL EXCISION OF INFECTED CORNEA W/ SUBSEQUENT TX.

43
Q

WHAT SHOULD BE AVOIDED IN TREATING AK & GAE

A

TOPICAL CORTICOSTEROIDS

44
Q

PROCEDURE OF CHOICE IN AK & GAE

A

DEEP LAMELLAR KERATECTOMY

45
Q

2 FORMS OF TROPHOZOITE OF NAEGLERIA FOWLERI

A

AMOEBOID

AMOEBOFLAGELLATE

46
Q

3 STAGES OF NAEGLERIA SPP.

A

CYST
TROPHOZOITE
FLAGELLATED

47
Q

ROUTE OF ENTRY OF N. FOWLERI

A

THRU OLFACTORY BULB

48
Q

ONLY NAEGLERIA SPECIES TO HAVE CAUSED DISEASE IN HUMANS

A

NAEGLERIA FOWLERI

49
Q

WHERE DO NAEGLERIA THRIVE BEST

A

THERMOPHILIC– HOT SPRINGS & WARM AQUATIC AREAS

50
Q

SYMPTOMS OF PAM ARE INDISTINGUISHABLE FROM

A

BACTERIAL MENINGITIS

51
Q

TX OF PAM

A

AMPHOTERICIN B + CLOTRIMAZOLE

52
Q

PROPHYLAXIS OF N. FOWLERI

A

EASILY KILLED BY CHLORINATION AT 1 PPM OR HIGHER