Haematuria and Urological Emergencies Flashcards
definition of haematuria
blood in the urine
- either microscopic or macroscopic
what is the diagnosis quota for haematuria
presence of 5 or more RBC per high-power field in 3 of 3 consecutive specimens obtained at least one week apart
what are the 2 categories of haematuria
visible/macroscopic/gross haematuria
non-visible/microscopic/dip-stick positive haematuria
what are the 2 categories of microscopic haematuria
symptomatic; hesitancy, frequency, urgency, dysuria
or
asymptomatic - incidental finding
what else can cause urine to be red that is not blood from urinary tract
Menstrual bleeding
Food - beetroot, blackberries, rhubarb
Myoglobin in urine - destruction of muscles, Crush syndrome
Drugs - Nitrofurantoin, Rifampicin, Chloroquine
Toxins - lead, mercury
what can cause brown coloured urine
urobilonogen in urine - hemolysis, liver dysfunction
porphyria
what can make people prone to bleeding
blood thinners - warfarin, heparin, aspirin
bleeding disorders
what percentage of people with frank haematuria will have cancer
20-30%
what percentage of people with microscopic haematuria will have cancer
asymptomatic + malignancy
- 2.6%
risk factors for malignancy
smoking history occupational exposure to chemical or dyes Hx of gross haematuria Age > 40 Hx of urological disorder/disease Hx of irritative voiding symptoms Hx of UTI Analgesic abuse
common infections that can cause blood in the urine
urethritis prostatitis cystitis ureteritis pyelonephritis glomerulonephritis
how can stones cause blood in the urine
kidney/ureter stones
on the way down can scratch mucous lining and cause bleeding
what Sx does renal tumour presents with
Haematuria - 50-60%
Pain - 40%
Kidney mass - 30-40%
Triad
how do tumours of urinary tract present
Haematuria - 75-85%
Retention of urine
Urinary irritative symptoms
Loin pain
what are the 2 types of cancers common in urology system
Renal Cell Carcinoma
Transition cell carcinoma
what is Sport haematuria
renal/bladder trauma from contact sports/running
what is the pathogenesis of sport haematuria
vasoconstriction of renal vessel
- hypoxic damage to nephrones
constriction of efferent glomerular arteriole
- increased filtration pressure
what is decompression haematuria
patient with retention, drained to quickly then some blood vessels with get broken and you get haematuria
what is pneumaturia
passage of gas mixed with urine, and may be as a result of a fistula between the bowel and the bladder
see bubbles in the urine
what is faecaluria
presence of fecal matter in the urine
What should be considered in the Hx of haematuria
Trauma Age Gender Nature of haematuria Smoking Occupation Country Urological Hx FH of malignancy Hx of bleeding disorders Phenacetin abuse Concomitant treatment e.g. Warfarin Recent symptoms suggesting UTI
what can the nature of the blood in the urine appear
dark red with clots
fresh red blood
dark red with wormlike clots with colic loin pain - ?
hematuria is coming from upper urinary tract
- blood from kidney, down the ureter
what are the timing stages of bleeding and what can it suggest
initial/start of void - suggest bleeding is coming from urethra or prostate gland
terminal/end of void
total/throughout void
what is seen in Egypt land water that can cause urinary problems
schistosoma
what flower is seen in china and can cause urinary problems
Aristolochia
what drug can cause Transition cell cancer if abused
phenacetin
Ix of haematuria
urinalysis
culture and sensitivity
cytology
tenderness in abdo
mass in abdo
prostate exam
frank haematuria urinary uregency + frequency smoker female - aged 24 sexually active USS + cytology normal
Diagnosis
UTI
frank haematuria urinary uregency + frequency smoker female - aged 40 paraplegic bladder stones USS + Cytology normal
Diagnosis
SCC in the bladder
frank haematuria urinary uregency + frequency smoker female - aged 60 USS normal cytology suspicious
Cancer
what is acute urinary retensiont and what causes it commonly
inability to urinate with increasing pain
complication of BPH
what are precipitated/triggering events of acute urinary retention
- non-prostate related surgery,
- catheterization or urethral instrumentation
- anaesthesia
- medication with sympathomimetic or anticholinergic effects
Tx of acute urinary retention
Catheter
Alpha blocker - Tamsulosin
who gets post-obstructive diuresis (peeing more)
chronic bladder outflow obstruction in association with uraemia, oedema, CCF, hypertension
Mx of post-obstructive diuresis
monitor fluid balance
beware urine output > 200ml/hf
usually resolves in 24-48hrs
if severe IV fluid and sodium replacement
DDx of acute loin pain
Ureteric colic secondary to calculus
Tx of stones that do not require surgery
NSAID +/- opiate
Alpha-blocker (Tamsulosin) for small stone expected to pass