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Cells > Haematopoiesis > Flashcards

Haematopoiesis Flashcards

1
Q

What does haematopoiesis mean?

A

The formation and development of blood cells

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2
Q

What makes up blood?

A

55% plasma
<1% buffy coat of white blood cells and platelets
45% red blood cells

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3
Q

What does Hct stand for?

A

Haematocrit

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4
Q

What does haematocrit mean?

A

The proportion of blood made up of red blood cell

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5
Q

What does RBC stand for?

A

Red blood cell count

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6
Q

What does Hb stand for?

A

Haemoglobin

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7
Q

What does MCV stand for?

A

Mean corpuscular volume

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8
Q

How do you calculate MCV?

A

Haematocrit divided by red blood cell count

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9
Q

What does mean corpuscular volume mean?

A

The average size of your red blood cells

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10
Q

What does MCH stand for?

A

Mean corpuscular haemoglobin

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11
Q

How do you calculate MCH?

A

Haemoglobin divided by red blood cell count

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12
Q

What does mean corpuscular haemoglobin mean?

A

The amount of haemoglobin per red blood cell

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13
Q

What does RDW stand for?

A

Red cell distribution width

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14
Q

What is erythropoiesis ?

A

The formation of red blood cells

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15
Q

What does EPO stand for?

A

Erythropoietin

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16
Q

How is erythropoeisis regulated?

A

Decreased O2 levels detected by kidneys
Erythropoietin (EPO) is produced and enters the bone marrow
Increased red blood cell production until O2 increases to capacity which then inhibits the formation of EPO

17
Q

What is the name of the main stem cell involved in formation of blood cells?

A

Multipotent hematopoietic stem cell

18
Q

What 2 stem cells does a multipotent hematopoietic stem cell differentiate into?

A

Common myeloid progenitor

Common lymphoid progenitor

19
Q

What blood cells are formed from a common myeloid progenitor?

A

Platelets, red blood cells, basophils, neutrophils, eosinophils, monocytes, mast cells, macrophage, myeloid dendritic cell

20
Q

What blood cells are formed from a common lymphoid progenitor?

A

B lymphocytes, T lymphocytes, plasma cells, natural killer cells, lymphoid dendritic cells

Cells (8 decks)

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