Haematology: pathognomonic findings Flashcards

1
Q

Howell-Jolly bodies

A

Any cause of asplenism/ splenic dysfunction:

  • Splenectomy
  • Splenic infiltration (eg leukaemia)
  • Splenic infarction/ sequestration (eg SCD)
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2
Q

Pappenheimer bodies

A

Myelodysplastic syndrome

also SCD, sideroblastic anaemia, haemolytic anaemia

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3
Q

Heinz bodies

A

G6PD

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4
Q

Smudge cells

A

CLL

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5
Q

Auer rods

A

AML (also have blast cells)

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6
Q

Teardrop shaped erythrocytes on blood film and a dry tap (unable to obtain bone marrow aspirate)

A

Myelofibrosis - will have bone marrow failure (pancytopenia)

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7
Q

Hypersegmented neutrophils

A

Megaloblastic anaemias: B12 / folate deficiency

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