Haematology: pathognomonic findings Flashcards
1
Q
Howell-Jolly bodies
A
Any cause of asplenism/ splenic dysfunction:
- Splenectomy
- Splenic infiltration (eg leukaemia)
- Splenic infarction/ sequestration (eg SCD)
2
Q
Pappenheimer bodies
A
Myelodysplastic syndrome
also SCD, sideroblastic anaemia, haemolytic anaemia
3
Q
Heinz bodies
A
G6PD
4
Q
Smudge cells
A
CLL
5
Q
Auer rods
A
AML (also have blast cells)
6
Q
Teardrop shaped erythrocytes on blood film and a dry tap (unable to obtain bone marrow aspirate)
A
Myelofibrosis - will have bone marrow failure (pancytopenia)
7
Q
Hypersegmented neutrophils
A
Megaloblastic anaemias: B12 / folate deficiency