Haematology HL Flashcards
Approach to anaemia
Causes of microcytic, disease pathophysiology, FBC, film and other findings
Causes of normocytic, disease pathophysiology, FBC, film and other findings
Causes of macrocytic, disease pathophysiology, FBC, film and other findings
cAUSES of PT, APTT, bleed time, fibrinogen, D dimer and common associated disease
Markers of ahemolusis
Causesof haemolysis
Describe the components and significance of FBC
Provide overview of aematopoiesis, cells and sites; lifecycles and functions
Describe the in vivo model of coagulation
Describe the in vitro model of coagulation
Describe the moa of common anticoags
Describe the moa of common Describe the moa of common anticoags
“ antiplatelets
Describe common adverse reactions associated with anticoags and antiplatelets
Describe coulter principle
Describe how FBc parametesrs are measured
Which coags are made by liver, which neeed K and which ahas shortes t t1/2
List three (min) chronic diseases and explain how they cayse anaemia
Provide overview of et, MF and PV
Describe the underlying genetics and mainfestiation of cml
Discuss dx and comps of cml
Describe how abo and rh work
Describe aiha and manifestations and dx/mx. Disntiguish with delayed
Describe rh disease and manifestations and dx/mx
Whats a massive transfusion and what are the complicatiosn
Describe direct combs and indirect
- Describe Patho-physiology
- Clinical features, and
- Basic laboratory diagnosis of:
i) Thalassaemia major
ii) Sickle cell disease
iii) Hereditary spherocytosis
iv) G6PD deficiency
Describing staging for lymphomas and broad amangemt
What are some causes of aplasia
Describe causes and presenataiton of aa
How to manage aa and issues
What is MDS, geatuers
Describe MDS management
Describe thrombocytopenia issues
Dsescribe work up for purpura and ppissble causes
Describe ITP
Describe hit
Describe DIC
Describe FACTOR V
Describe cancer and lupus in thrombocutosis
Describe diagnostic appraich to thrombocytosis
Whena re blodod product indicated
Describe haemophilai and vqf
Describe bloods of liver, hiv, mal, chronic
Distinguish between MGUS, MM, smoudlering and approach to treat MM
Describe Virchow and distinguish between arterial and venous thrombo
How ti investigate tphilia
Role of serum protein ephoresis and proteins measured
Interpret ephoresis and immunofiation, role og these
Ddx for acute haemolutics
What is massive tfusionand comps