Haematology Flashcards
1
Q
Bone marrow failure (pancytopenia) and circulating blast cells in the blood. What’s the most likely diagnosis?
A
AML
2
Q
The translocation t9:22 (Philadelphia chromosome) is typically found in?
A
CML
3
Q
Lytic lesions and oligoclonal IgG band are typically found in?
A
Multiple myeloma
4
Q
What is the treatment for myeloma?
A
Chemotherapy
And treat bone probs e.g. bisphosphonates, analgesia
5
Q
T/F: amyloidosis is a recognised complication of myeloma
A
True
6
Q
A bone marrow aspirate is used to confirm the suspicion of myeloma by demonstrating what?
A
an excess (>10%) plasma cells
7
Q
Primary polycythaemia is due to a haematopoietic stem cell defect, almost always as a result of a mutation in what gene?
A
JAK2 gene
