Haematology

Question 1

Schilling’s test

Answer 1

B12 deficiency

Question 2

Schistocytes

Answer 2

Intravascular haemolysis

Question 3

Philadelphia chromosome (9 and 22 translocation)

Answer 3

Chronic myeloid leukaemia

Question 4

Translocation between chromosomes 8 and 14

Answer 4

Burkitt’s lymphoma

Question 5

Russell bodies

Answer 5

Chronic inflammation

Question 6

Young boy with reduced Factor VIII and increased APTT

Answer 6

Haemophilia A

Question 7

Pepper pot skull/lytic lesions

Answer 7

Myeloma

Question 8

Auer Rod cells

Answer 8

Acute myeloid leukaemia

Question 9

Congo red staining

Answer 9

Amyloid deposition of biopsied tissue in myeloma and amyloidosis

Question 10

Itchy after a hot bath

Answer 10

Polycythaemia rubra vera

Question 11

Haemarthrosis

Answer 11

Haemophilia

Question 12

Reduced levels of Factor IX with Christmas disease

Answer 12

Haemophilia B

Question 13

Atypical lymphocytes

Answer 13

Epstein-Barr virus

Question 14

JAK2 mutation

Answer 14

PRV or essential thrombocythaemia

Question 15

Hair on end skull x-ray

Answer 15

Beta thalassaemia major

Question 16

Positive Schumm’s test

Answer 16

Intravascular haemolytic anaemia

Question 17

Bence Jones proteins

Answer 17

Myeloma

Question 18

Reed-Sternberg cells

Answer 18

Hodgkin’s lymphoma

Question 19

Bite cells, blister cells and Heinz bodies

Answer 19

G6PD deficiency

Question 20

Smudge cell (immature leukocytes)

Answer 20

Chronic lymphocytic leukaemia

Question 21

Rouleaux formation

Answer 21

Myeloma

Question 22

Lymphadenopathy made worse with alcohol

Answer 22

Hodgkin’s lymphoma

Question 23

Tear drop shaped red blood cells and a leukoerythroblastic appearance

Answer 23

Myelofibrosis