Haematology Flashcards
What oral health implications does warfarin have?
Blood thinner - may take longer to achieve haemostasis for extractions
What oral health implications does simvastatin have?
May cause dry mouth - greater risk of caries or gum disease
What oral health implications does Furosemide have
may cause dry mouth
What oral health implications does metformin have?
dry mouth
Haemophilia A cause
- Factor VIII deficiency
Haemophilia B
Factor IX deficiency
Von Willebrand’s disease
- reduced factor VIII level
- reduced platelet aggregation
Warfarin mechanism of action
inhibits production of vitamin K dependent clotting factors
How often should the iNR be checked in a patient on warfarin?
every 4-8 weeks
INR normal reading
2-3
INR stands for,,,
international normalised ratio
DOAC mechanism of action
inhibition of factor X
Examples of DOACs
- rivaroxiban
- apixaban
- edogaban
- dabigatran
DOACs that needs to be taken twice daily
apixaban and dabigatran
what type of drug is warfarin?
anti coagulant
Management of a patient on warfarin prior to extraction
check INR no more than 24 hours before procedure (72 hours if patient stably anti coagulated)
if INR below 4 - treeat
delay if over 4
Management of a patient on apixaban prior to extraction
miss morning dose
take dose 4 hours after haemostasis is achieved
Management of a patient on rivaroxaban or edoxaban prior to extraction
delay morning dose
- take 4 hours after haemostasis achieved (rivaroxiaban) or usual time in evening (edoxaban)
