Haematology

Question 1

Pepper pot skull/lytic lesions

Answer 1

Myeloma

Rouleaux formation also a nice big clue

Question 2

Congo red staining

Answer 2

amyloid deposition of biopsied tissue in Myeloma and AA

amyloidosis

Question 3

Reed-Sternberg cells

Answer 3

Hodgkin’s Lymphoma

Question 4

Philadelphia Chromosome (9;22 translocation)

Answer 4

Chronic Myeloid Leukemia

Question 5

Atypical Lymphocytes

Answer 5

EBV (mononucleosis)

Question 6

Auer rods

Answer 6

Acute Myeloid Leukaemia

Question 7

Bence-Jones Proteins

Answer 7

Multiple Myeloma

Question 8

“ Itchy after a hot bath”

Answer 8

Polycythaemia Rubra Vera

Question 9

Translocation (8;14)

Answer 9

Burkitt’s lymphoma

Question 10

Alcohol makes it worse

Answer 10

Hodgkins lymphoma

Question 11

Haemarthrosis

Answer 11

Haemophilia

Question 12

Reduced levels of factor IX with Christmas Disease

Answer 12

Haemophilia B

Question 13

Young boy with reduced levels of factor VIII and an increased APTT

Answer 13

Haemophilia A

Question 14

Schillings Test

Answer 14

B12 deficiency

Question 15

Smudge cells (immature leukocytes)

Answer 15

CLL (chronic lymphoblastic leukaemia)

Question 16

JAK-2 mutation

Answer 16

PRV or essential thrombocythemia

Question 17

NBT test

Answer 17

CGD

Question 18

Positive Schumm’s test

Answer 18

Intravascular Haemolytic anaemia

Question 19

Hair-on-end skull X-ray

Answer 19

Major beta-thalassaemia

Question 20

Bite cells, blister cells and Heinz bodies

Answer 20

G6PD deficiency

Question 21

Russell bodies

Answer 21

chronic inflammation

Question 22

Schistocytes

Answer 22

intravascular haemolysis