HAEM Rx Flashcards

1
Q

Hereditary Spherocytosis

A

Folic acid
Blood transfusion
Splenectomy

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2
Q

Sickle cell disease

A

Prophylaxis

  • Vaccination
  • Folic acid
  • Malarial prophylaxis

Acute

  • Hydration
  • Oxygen
  • Abx
  • Analgesia

Disease modifying drugs
- hydroxycarbamide

Blood transfusions

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3
Q

Alpha / Beta Thalassaemia

A

Iron + folic acid supplements
Life-long blood transfusions
Iron chelation therapy - Deferiprone
Splenectomy

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4
Q

Hypochromic microcytic anaemia

A

Iron + vitamin C supplements

OCP

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5
Q

Normochromic normocytic anaemia

A

Treat underlying disease

Corticosteroids

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6
Q

Macrocytic anaemia

A

Vitamin B12 and folate supplement

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7
Q

Haemolytic anaemia

A

Folic acid
Blood transfusion
Immunosuppression (steroids)
Treat underlying disease

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8
Q

Venous Thromboembolism

A

LMWH, warfarin, direct oral anticoagulants

Thrombolysis

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9
Q

Arterial Thromboembolism

A

LMWH, warfarin, aspirin, clopidegrol

Thrombolysis

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10
Q

Disseminated Intravascular Coagulation

A

Platelets, fresh frozen plasma
Antithrombin
Prophylaxis w/ anticoagulants - LMWH, warfarin

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11
Q

Haemophilia A

A

Factor VIII

Tranexamic acid

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12
Q

Haemophilia B

A

Factor IX

Tranexamic acid

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13
Q

Von Willlebrand Disease

A

Von Willebrand factor concentrate
Tranexamic acid
OCP

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14
Q

Thrombocytopenia

A

Blood transfusions / platelets

Plasma exchange (thrombotic thrombocytopenia)

Aspirin + hydroxycarbamide (essential thrombocytopenia)

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15
Q

Non-Hodgkins Lymphoma

A

Anti-CD20 monoclonal antibodies

Chemotherapy

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16
Q

Hodgkins Lymphoma

A

Anti-CD30 monoclonal antibodies
Chemotherapy
Radiotherapy
Immunotherapy

17
Q

Immune Thrombocytopenic Purpura

A

Corticosteroids - methotrexate / prednisolone
IV IgG
Splenectomy
Thrombopoeitin analogues

18
Q

Polycythemia Vera

A

Venesection

Aspirin, hydroxycarbamide, ruxolitinib

19
Q

Idiopathic Myelofibrosis

A

Blood transfusions for anaemia

Ruxolitinib