Haem: Interpreting Blood Films Flashcards
Hypochromia
IDA, thalassaemia
Hyperchromia
Megaloblastic anaemia, hereditary spherocytosis
Ansiochromia
Sideroblastic anaemia, iron treatment for IDA, hypochromic anaemia following treatment
Polychromoatophilia
Reticulocytosis, haemolytic, acute blood loss
Microcytosis
IDA, thalassaemia, ACD, sideroblastic anaemia
Macrocytosis
Megaloblastic anaemia, myelodysplastic syndrome, alcoholism, liver disease
Eliptocytes
Hereditary eplitocytosis, IDA, myelofibrosis with myeloid metaplasia, megaloblastic anaemia, SCA
Spherocytes
Hereditary spherocytosis, AIHA, direct physical injury
Codocytes/Target Cells
Thalassaemia, chronic liver disease, IDA, haemoglobinopathies, post-splenectomy
Schistocytes
Thalassaemia, megaloblastic anaemia, MAHA
Acanthocyte
Abetalipidproteinaemia, liver disease, membrane abnormalities, splenectomy
Echinocytes/Burr Cells
Artefact, uraemia, GI bleeding, stomach carcinoma
Keratocytes
Mechanical damage, Heinz body removal
Stomatocytes
Hereditary stomatocytosis, alcohol abuse, liver disease, myelodysplastic syndrome
Tear-drop Cells
Myelofibrosis, thalassaemia, haemoglobinopathies
Basophilic Stippling
Lead poisoning, megaloblastic anaemia, thalassaemia, liver disease, myelodysplasia
Howell-Jolly Bodies
Post-splenectomy, megaloblastic anaemia, haemolytic anaemia, abnormal erythropoesis
Heinz Bodies
Post-splenectomy, G6PD deficiency, glutathione synthase deficiency, drugs, chronic liver disease
Rouleaux
Paraproteinaemia, myeloma, chronic inflammation
Reticulocytes
Haemolytic anaemia
Right Shift
Megaloblastic anaemia, uraemia, liver disease
Left shift
Acute infection
Pelger-Heüt Cells
Congenital lain B receptor mutation, myelogenous leukaemia, myelodysplastic syndromes
Hypersegmented Neutrophils
Megaloblastic anaemia, uraemia, IDA
