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Fred's Pathology > Autoantibodies > Flashcards

Autoantibodies Flashcards

1
Q

Antiphospholipid syndrome is associated with which autoantibodies?

A

Cardiolipin
Beta-2 glycoprotein
Lupus anticoagulant

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2
Q

Autoimmune hepatitis is associated with which autoantibodies?

A

Anti-smooth muscle antibody
Anti-Liver Kidney Microsomal-1 (Anti-LKM-1)
Anti-Soluble Liver Antigen (Anti-SLA)

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3
Q

Autoimmune haemolytic anaemia is associated with which autoantibodies?

A

Anti-Rh blood group antigen

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4
Q

Autoimmune thrombocytopenia purpura is associated with which autoantibodies?

A

Anti-glycoproetin IIb/IIIa or Ib-IX antibody

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5
Q

Churg-Strauss syndrome is associated with which autoantibodies?

A

p-ANCA

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6
Q

Coeliac disease is associated with which autoantibodies?

A

Anti-tissue transglutaminase

Anti-endomysial antibody

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7
Q

Congenital heart block in infants born to SLE mothers is associated with which autoantibodies?

A

Anti-Ro

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8
Q

Dermatitis herpetiformis is associated with which autoantibodies?

A

Anti-endomysial antibody

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9
Q

Dermatomyositis is associated with which autoantibodies?

A

Anti-Jo-1 (t-RNA synthase)

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10
Q

Diffuse cutaneous scleroderma is associated with which autoantibodies?

A

Topoisomerase/Scl70
RNA Pol I, II, III
Fibrillarin

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11
Q

Goodpasture’s syndrome is associated with which autoantibodies?

A

Anti-GBM

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12
Q

Graves disease is associated with which autoantibodies?

A

Anti-TSH receptor

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13
Q

Hashimoto’s thyroiditis is associated with which autoantibodies?

A

Thyroglobulin

Thyroperoxidase

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14
Q

Limited cutaneous scleroderma is associated with which autoantibodies?

A

Anti-centromere antibody

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15
Q

Microscopic polyangitis is associated with which autoantibodies?

A

p-ANCA

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16
Q

Mixed connective tissue disease is associated with which autoantibodies?

A

Anti-U1RNP antibody

17
Q

Myasthenia gravis is associated with which autoantibodies?

A

Anti-ACh receptor antibody

18
Q

Pernicious anaemia is associated with which autoantibodies?

A

Antibody to gastric parietal cells

Antibody to intrinsic factor

19
Q

Polymyositis is associated with which autoantibodies?

A

Anti-Jo-1

20
Q

Primary billiary cirrhosis is associated with which autoantibodies?

A

Anti-mitochondrial antibodies

21
Q

Rheumatoid arthritis is associated with which autoantibodies?

A

Anti-CCP

Rheumatoid factor

22
Q

Sjogren’s syndrome is associated with which autoantibodies?

A

Anti-Ro
Anti-La
RF

23
Q

SLE is associated with which autoantibodies?

A 
dsDNA
Histones
Anti-Ro
Anti-La
Anti-Sm
Anti-U1RNP
24
Q

Type 1 DM is associated with which autoantibodies?

A

Glutamate decarboxylase

Pancreatic beta cells

25
Q

Wegner’s granulomatosis is associated with which autoantibodies?

A

c-ANCA

Fred's Pathology (3 decks)

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