H1 Flashcards
1
Q
What is the main function of bone marrow?
A
Haemopoesis
2
Q
Define haemopoesis
A
Production of all cellular components of blood and plasma
3
Q
Where are blood cells produced during foetal life?
A
- 0-6 weeks: yolk sac
- 6 weeks-6 months: liver, spleen
- 6 months-birth: bone marrow
4
Q
Where are blood cells in children up to 5 years old?
A
All bones (red bone marrow)
5
Q
Where are blood cells produced in adults?
A
- Red marrow in axial skeleton
- Slowly replaced by yellow marrow (fat) with age
- Under stress, liver and spleen produce blood cells
6
Q
Name the 3 cell lines
A
erythrocytes (RBC)
leucocytes (WBC)
thrombocytes (platelets)
7
Q
What is the function of leucocytes?
A
Important immune function
8
Q
What is the function of platelets?
A
haemostasis: prevents and stops bleeding
9
Q
What is the role of bone marrow in blood cell development?
A
Site of haemopoesis, produces multipotent stem cells that differentiate into blood cells
10
Q
What are the key components of haemostasis?
A
- constriction of damaged vessel
- platelet plug formation: adhesion of platelets to damaged epithelium
- clot formation: changing of fibrinogen to fibrin by clotting factors
