H pylori and tings Flashcards
simple lifestyle to promote ulcer healing
stop smoking
antiacids and antisecretory drugs too
what is step one of HP treatment and for how long
ONE WEEK TRIPLE THERAPY
PPI
clarythromycin
and either amox or metronidazole
what might affect your choice of antibiotic to use in HP
if patient has previously treated with metronidazole you wouldnt use the metronidazole option - use amox instead
if treated with macrolide recently dont use clarythromycin, use amox & metro
do you usually continue the PPI/H2 antag after eradication treatment ?
no - unless the ulcer is large then continue for three months
out of the three HP eradication antibacterial options which is the only one where resistance developping is unlikely
amox
is dual therapy for HP an option
nooooo - poor eradication results
triple therapy gets about 85%
if triple therapy HP erradication fails what would you throw at it
two weeks of PPI tripotassium dicitratobismuthate tetracycline metronidazole
alternatively get senstivety tested with endoscopy
if using H2 to prevent NSAID associated ulcer what should you do to the dose
double the daily dose
misoprostol can be used to prevent NSAID associated ulcers but what limits its use
colic and diahhorea
what do you treat nsaid associated ulcers with
PPIs and stop NSAID
then test for H pylori and treat that too
If you cant stop the NSAID just use PPI to treat
councelling with milk and tripotassium dicitratobismuthate
what class of drug is this
dont drink mild during treatment but you can have a wee bit in drinks or on cereal
antacids and fruit juice to be avoided 30 mins before dose
its a chelate/complex thing
councelling for sucralfate and what type of drug is this
risk of bezor with enteral feeds - separate by one hour
its a chelate/complex thing
what is the drug class of choice for zollinger ellison sydrome
PPIs ( more effctive than H2 antag)
what is the main sideeffect caution in the bnf for H2 antag
pyschiatric reactions
age for ranitidine otc
maximum duration
16
2 weeks
75mg dose
