Bowel Flashcards
what antibiotics cause c diff (5)
quinilones clindamycin cephlasporins (second and third gen) ampicillin/ amoxicillin co-amox
antispasmodics which slow gut transit e.g. codeine are contrainditcated in diverticular disease because
they can exacerbate symptoms
what sort of fiber should people with IBS use
soluble - e.g. ispagula husk
not insoluble like bran
what sort of laxative is preffered in IBS
osmotic such as macrogol
but lactulose may cause bloating
in IBS patients who have not responded to antispasmodic drugs for abdo pain what can be tried
TCA
or later SSRI
what type of drug is mesalazine
aminosalicylate
is cuclosporin used for crohns or UC
UC
what is the connection between smoking and chrons
smoking cessation reduces the risk of relapse
What two antibiotics are used for fistulating crohns disease
metronidazole and cirpofloxacin
what is the risk of metronidazole use in fistulating crohns
what duration do we limit it to
peripheral neuropathy
usually 1 month, at most 3 months
do we use antispasmodic or antimotility drugs in IBD
no - may percipitate mega colon (includes loperamide, codeine etc) treatment of the inflamation is more logical
what is colestyramine used for in IBD
diarrhoea resulting from loss of bile salt absorption (as cholestytamine binds bile salts)
which aminosalicylate is older, activates further up the bowel and therefore has more sulfonamide like side-effects
sulfasalazine
as opposed to new ones: mesalazine, besalazine, osalazine
what significant 2 side-effectds are common to all aminosalycilates
blood disorders and lupus like syndrome
what are the sulfonamide like sideeffects of aminosalycilates
Diarrhea. dizziness. loss of appetite. nausea or vomiting. tiredness