H. pylori

Question 1

Two likely differential diagnosis for heartburn?

Answer 1

GORD and peptic ulcer disease- H.pylori

Question 2

Lifestyle measures to treat heart burn?

Answer 2

eat small frequent meals at regular intervals, avoid eating at night, reduce fatty foods, avoid alcohol and smoking, lose weight

Question 3

Name two treatments for heart burn

Answer 3

PPI and H2 receptor antagonist

Question 4

OGD shows metaplastic changes in the distal oesophagus. What is the likely diagnosis and why is this significant?

Answer 4

Barett’s oesophagus- can progress to oesophageal adenocarcinoma

Question 5

What is the treatment of H.pylori infection?

Answer 5

2 weeks of clari and amox with omeprazole BD

Question 6

Which antibiotics are used to treat H.pylori infection?

Answer 6

clarithromycin or metronidazole AND amoxicillin

Question 7

Describe the features of H.pylori bacteria

Answer 7

gram negative, helical-shaped, possess flagella, and is found in the stomach

Question 8

When is best to take PPI and why?

Answer 8

first thing in morning, must be taken on empty stomach and proton pumps are most active in the morning

Question 9

What is the triad of treatment for H.pylori infection?

Answer 9

omeprazole, amoxicillin, and clarithromycin

Question 10

Investigations for h.pylori?

Answer 10

urea breath test and stool antigen tests