H&N cancer high yield

Question 1

premalignant lesions

Answer 1

o Leukoplakia: white patches that do not rub off

o Erythroplakia: red velvety patches; not due to another condition

Question 2

most common tumor of H&N

Answer 2

oropharyngeal cancer, squamous cell type

HPV associated

Question 3

oral squamous cell cancer

Answer 3

HPV related
young adults, M>F
presents as neck mass
good prognosis

Question 4

laryngeal squamous cell carcinoma

Answer 4

hoarseness and alteraion of voice; thorat pain, dysphagia
glottic is most common
supraglottic (foreign body sensation, pain, hemoptysis, muffled voice)

Question 5

salivary gland tumors

Answer 5

mucoepidermoid is most common (facial nerve involvement)
adenoid cystic carcinoma (invades nerves–>nerve sx)
acinic cell carcinoma (parotid, pts require long term follow-up)

Question 6

nasopharyngeal carcinoma

Answer 6

china, eskimos
most common neck mass
presents w/ unilateral hearing loss, otitis media
nonkeratinizing SCC has better prognosis

Question 7

sinonasal adenocarcinoma

Answer 7

woodworkers! all are aggressive

unilateral nasal obstruciton, epistaxis, pain for a few months

Question 8

nasal type angiocentric NK/T cell lymphoma

Answer 8

aggressive lymphoma w/ poor prognosis
insidious
atypical lymphoid infiltrate, CD56+, EBV+
vessel occlusion–>necrosis

Question 9

olfactory neuroblastoma

Answer 9

bimodal
nasal obstruction, epistaxis
cells in neurofibrillar matrix forming rosettes