H: Immune system Flashcards

1
Q

Identify

A

Lymphocyte

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2
Q

Identify

A

Thymus
C: capsule
Cx: cortex
M: medulla
S: interlobular septa

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3
Q

Identify structures in this section of the medulla of thymus

A

Dark blue spots: lymphocytes
Ep: epithelial cells
H: Hassal’s corpuscles - keratinised epithelial cells

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4
Q

Identify structures in this young cortex of thymus

A

Dark blue = lymphocytes
Light pink = reticular

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5
Q

Identify

A

Lymph node
C = capsule
S = subcapsular sinus
E = endothelial cells lining sinus
M= macrophages

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6
Q

Identify

A

Lymph node
C = capsule
T = trabeculae
S = subcapsular sinus
Cx = cortex
M = medulla
F = follicles with germinal centres (actively dividing B cells) surrounded by resting B cells.
P = paracortex with T cells
M = medulla
MC: medullary cords - have mature B cells

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7
Q

Medullary sinuses?

A

Spaces between medullary cords

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8
Q

Spleen

A

Largest lymphoid organ
Removes blood-borne antigens and old/defective RBCs
Site of hematopoiesis in fetus.

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9
Q

Function of white and red pulp in spleen?

A

White = thick sleeves of lymphoid tissue
Red = Surrounds white pulp, composed of splenic cords and venous sinuses.

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10
Q

Identify structures in spleen

A

WP: white pulp
RP = red pulp
C = capsule
T = trabeculae

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11
Q

White pulp in spleen

A

T cells around arteries
B cells form follicles

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12
Q

Red pulp in spleen

A

Splenic sinusoids with macrophages (sinusoid = leaky capillary)
Splenic cords (sheets of reticular CT)

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13
Q

Splenic artery division

A

Splenic artery –> central artery –> sheathed capillaries –> blood emptied into red pulp and enters sinusoids.

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14
Q

Identify

A

Palatine tonsil
E = stratified squamous epithelium
White spaces = crypts, where pus will accumulate if sick
Cap = Hemi-capsule
F = follicles with germinating entres.

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15
Q

Peyer’s patches - where are they found + what do they contain?

A

Found in distal small intestine wall
Have clusters of lymphoid follicles with germinal centres

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16
Q

Identify

A

Peyer’s patch
Gc = germinal centre

17
Q

Identify

A

Neutrophils

18
Q

Identify

A

Eosinophils

19
Q

What are primary lymphoid tissue functions?

A

immature lymphocytes acquire receptors to recognise antigens.

20
Q

Two types of primary lymphoid tissue + their functions:

A

Thymus: maturation of T lymphocytes
Bone marrow: maturation of B lymphocytes.

21
Q

Secondary lymphoid tissue function:

A

Lymphocytes are activated in response to antigen

22
Q

Examples of secondary lymphoid tissue

A

Lymph nodes, spleen, mucosal associated lymphoid tissue (MALT) e.g. tonsils, Peyers Patches

23
Q

Contents of thymus:

A

Cortex: less mature T cells
Medulla: more mature T cells
Contains lymphocytes, macrophages and reticular cells