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Question 1

Which condition will cause increase in bone marrow production of neutrophils resulting to neutrophils?
a. Strenuous exercise
b. Pregnant woman in labor
c. Acute infection
d. Tachycardia

Answer 1

c. Acute infection

Question 2

Which finding is not consistent with leukemoid reaction?
a. Absence of eosinophils
b. LAP score of more than 100
c. Absence of basophils
d. Few neutrophils with bilobed nuclei

Answer 2

d. Few neutrophils with bilobed nuclei

Question 3

The following are performed to determine the LAP score, except:
a. 100 neutrophils are counted
b. Grading the staining reaction from 0-4+
c. Band forms are also counted to complete 100 cells
d. None of the choice

Answer 3

d. None of the choice

Question 4

Severe chronic neutropenia is defined as
a. Agranulocytosis for at least 6 months
b. Neutrophil count of <2 x 10^9/L for 1 month
c. Neutrophil count of <2 x 10^9/L for at least 6 Months
d. None of these

Answer 4

a. Agranulocytosis for at least 6 months

Question 5

Frequently this is the first sign of recovery from an acute overwhelming infection with agranulocytosis
a. Absolute monocytosis
b. Relative monocytosis
c. Toxic granules
d. Absolute count of < 1.1 x 10^9/L

Answer 5

b. Relative monocytosis

Question 6

Lymphocytosis with morphologic alteration will be seen in the following cases except in
a. Infectious mononucleosis
b. Viral influenza
c. Pertussis
d. CMV Infection

Answer 6

c. Pertussis

Question 7

Eosinophils may be seen in the following cases except in
a. CML
b. Parasitic infection
c. Allergic conditions
d. None of these

Answer 7

d. None of these

Question 8

A patient who is on steroid therapy will have
a. Monocytopenia
b. Lymphocytosis
c. Monocytosis
d. B and C

Answer 8

a. Monocytopenia

Question 9

Small, oval, pale blue structures that are peripherally located in the cytoplasm and seen only in neutrophils are most probably
a. Dohle inclusion bodies
b. Inclusions in May-hegglin anomaly
c. Phagocytic vacuoles
d. Autophagocytic vacuoles

Answer 9

a. Dohle inclusion bodies

Question 10

True of toxic granulations except:
a. They are peroxidase positive
b. Inversely proportional to CRP level
c. Seen also in band form and metamyelocytes
d. Should be differentiated from Reiley bodies

Answer 10

b. Inversely proportional to CRP level

Question 11

A Blood smear with myeloid cells that are seen in various stages of maturation from the most immature composed of occasional blasts to the most mature has what degree of left shift?
a. Mild left shift
b. Moderate left shift
c. Marked left shift
d. No left shift

Answer 11

c. Marked left shift

Question 12

Vacuoles in neutrophils that are formed due to effect of EDTA are
a. Smaller than phagocytic vacuoles
b. Usually 6 um in size
c. Formed only in patients with spesis d. None of these

Answer 12

a. Smaller than phagocytic vacuoles

Question 13

Reactive lymphocytes appear with increased basophilia of the cytoplasm due to:
a. Increased cytoplasmic RNA
b. Engulfed bacteria in the cytoplasm
c. Defective fusion of phagosome and lysosome
d. None of these

Answer 13

a. Increased cytoplasmic RNA

Question 14

Pince nez appearance in Pelger_huet anomaly is due to mutation in:
a. LYST gene
b. Lamin B receptor gene
c. NADPH oxidase gene
d. IL-2 receptor gene

Answer 14

b. Lamin B receptor gene

Question 15

Which finding will favor Pelger-Huet anomaly over other conditions that will cause neutrophils to have pince-nez appearance?
a. >20% of neutrophils are with bilobed
b. >80% of neutrophils are with bilobed nuclei
c. <50% of neutrophils are with bilobed nuclei
d. >40% of neutrophils are with bilobed nuclei

Answer 15

b. >80% of neutrophils are with bilobed nuclei