gynae oncology

Question 1

ovarian cancer - investigation

Answer 1

CA125 (~false +)
raised - urgent USS abdo + pelvis

calculate RMI - U x M x CA125
USS score
menopausal status
serum CA125

confirmation - diagnostic laparotomy or MRI

Question 2

ovarian cancer - symptoms + prognosis

Answer 2

asymptomatic
bloating / distension
abdo/pelvic pain
early satiety
ascites on USS
urinary symptoms
diarrhoea

usually 60y; poor prognosis as late diagnosis

Question 3

ovarian cancer - RFs

Answer 3

subfertility
many ovulations - early menarche, late menopause, nulliparity
FH BRCA mutations

Question 4

ovarian cancer on USS

Answer 4

ovarian cysts that are large, bilateral, complex (solid + cystic areas)

Question 5

ovarian cancer - treatment

Answer 5

surgery + platinum-based chemo - order depends