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Reproduction > Gyn > Flashcards

Gyn Flashcards

1
Q

Lichen Sclerosis

A

thin epidermiscollagenized dermishyperkeratosis - thickening stratum corneumatrophy in stromashrinkage of introitusinflammation (autoimmune) - responds to steriodsKraurosis vulvaepainful intercourse, itching, irritationsquamous carcinoma 1-4%

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2
Q

Squamous Hyperplasia

A

lichenification (thickening or hardening) process of squamous epitheliumopposite of lichen sclerosisleukoplakia = white discolorationhyperkeratosis present above THICKENED epidermis (acanthosis)chronic inflammatory statepink-white lesion, thicker than lichen sclerosisitching - it itches, they rub on it and the epithelium thickensbiopsy to r/o neoplasm

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3
Q

LSIL Characteristics

A

low NC ratioAbnormally shaped nucleusNuclear enlargementHyperchromoplasiaIrregularityperinuclear halo with distinct borders - koilocytes

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4
Q

HSIL Characteristics

A

Less cytoplasmHigh N:C ratiosmaller cellsif you can see the nucleolus, worry about invasion

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5
Q

Cervical Squamous Cancer Characteristics

A

irregular shapeprominent macronucleusgranular chromatinsimilar to HSILnucleoli may be presentinflammatory/necrotic background - tumor diathesis

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